Combipres Eye Drop 0.2%+0.5% is a combination ophthalmic solution containing Brimonidine Tartrate 0.2% and Timolol Maleate 0.5%. It is indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension who require combination therapy. By combining two medicines with different mechanisms of action, Combipres Eye Drop provides effective and sustained control of intraocular pressure, helping protect the optic nerve and reduce the risk of progressive vision loss.

Elevated intraocular pressure is a major risk factor for glaucoma, a condition that can cause irreversible damage to the optic nerve if left untreated. Maintaining appropriate eye pressure is essential to preserve vision and slow the progression of glaucoma.

Brimonidine Tartrate is an alpha-2 adrenergic receptor agonist that lowers intraocular pressure by reducing the production of aqueous humor while also increasing its drainage through the uveoscleral pathway. Timolol Maleate is a non-selective beta-adrenergic blocker that decreases the production of aqueous humor within the eye. Together, these medications provide greater intraocular pressure reduction than either medicine alone.

Combipres Eye Drop is intended for regular use as prescribed by an ophthalmologist. Consistent treatment and routine eye examinations are important for effective glaucoma management and long-term preservation of vision.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Combipres Eye Drop is indicated for:

• Open-angle glaucoma
• Ocular hypertension
• Reduction of elevated intraocular pressure in patients requiring combination therapy

How Combipres Eye Drop Works

• Brimonidine Tartrate reduces aqueous humor production and enhances uveoscleral outflow, lowering intraocular pressure.
• Timolol Maleate reduces the production of aqueous humor by blocking beta-adrenergic receptors in the ciliary body.

Together, they effectively reduce intraocular pressure and help protect the optic nerve from glaucoma-related damage.

Benefits of Combipres Eye Drop

• Effectively lowers elevated intraocular pressure.
• Combines two complementary glaucoma medications in one formulation.
• Helps reduce the risk of optic nerve damage and vision loss.
• Suitable for patients requiring combination therapy.
• Provides sustained intraocular pressure control.
• Convenient single-eye drop formulation.
• Supports long-term glaucoma management.

Dosage and Administration

Use Combipres Eye Drop exactly as prescribed by your healthcare provider.

• Instill one drop into the affected eye(s) twice daily, approximately 12 hours apart, or as directed by your ophthalmologist.
• Wash your hands before and after use.
• Avoid touching the dropper tip to the eye or any surface to prevent contamination.
• Close your eyes gently and apply pressure to the inner corner of the eye (nasolacrimal occlusion) for 1–2 minutes after instillation to reduce systemic absorption.
• If using other eye medications, wait at least 5–10 minutes between applications.
• Remove contact lenses before use and reinsert them at least 15 minutes after instillation if advised by your healthcare provider.

Possible Side Effects

Like all medicines, Combipres Eye Drop may cause side effects, although not everyone experiences them.

Common side effects include:

• Eye redness
• Burning or stinging sensation
• Dry eyes
• Blurred vision (temporary)
• Eye irritation
• Dry mouth
• Drowsiness
• Headache

Serious side effects may include:

• Severe allergic eye reactions
• Slow heart rate (bradycardia)
• Low blood pressure
• Difficulty breathing or worsening asthma
• Heart failure symptoms
• Severe eye pain or vision changes

Seek immediate medical attention if you experience chest pain, difficulty breathing, fainting, severe eye pain, sudden vision changes, or signs of a serious allergic reaction.

Precautions and Warnings

Before using Combipres Eye Drop, inform your healthcare provider if you have:

• Asthma or chronic obstructive pulmonary disease (COPD)
• Slow heart rate, heart block, or heart failure
• Low blood pressure
• Depression
• Diabetes
• Thyroid disorders
• Liver or kidney disease
• Pregnancy or breastfeeding

Inform your healthcare provider about all medications you are taking, especially beta-blockers, antihypertensive medicines, antidepressants, or other glaucoma medications.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

Store below 30°C in a cool, dry place, protected from direct sunlight. Keep the bottle tightly closed when not in use. Do not use the eye drops after the expiry date or beyond the recommended period after opening the bottle. Keep out of the reach of children.

Disclaimer

Combipres Eye Drop 0.2%+0.5% is a prescription ophthalmic medicine and should only be used under the supervision of a qualified ophthalmologist or healthcare professional. It is intended for ophthalmic use only. Regular eye examinations and intraocular pressure monitoring are recommended during treatment.