Doxofyl SR Tablet 400 mg contains Doxophylline in a sustained-release (SR) formulation, designed for prolonged bronchodilation in patients with asthma and chronic obstructive pulmonary disease (COPD). The sustained-release technology allows gradual release of the drug, providing long-lasting relief from airway obstruction and improving patient compliance with once or twice daily dosing.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each sustained-release tablet contains:

• Doxophylline 400 mg (SR formulation)

This formulation ensures controlled drug release for extended therapeutic action.

Indications

Doxofyl SR Tablet is indicated for:

• Bronchial asthma
• Chronic obstructive pulmonary disease (COPD)
• Chronic bronchitis
• Bronchospasm associated with respiratory disorders
• Maintenance therapy for chronic airway obstruction

It is not intended for rapid relief of acute asthma attacks.

Pharmacological Action

Doxophylline is a xanthine derivative that acts as a bronchodilator:

• Inhibits phosphodiesterase enzymes, increasing intracellular cyclic AMP (cAMP)
• Relaxes bronchial smooth muscles and widens airways
• Improves airflow and oxygen exchange
• Provides bronchodilation with fewer cardiovascular and CNS side effects compared to theophylline

The sustained-release formulation ensures stable plasma levels and prolonged action.

Dosage & Administration

• Dosage is individualized based on patient condition and physician advice
• Commonly taken once or twice daily
• Swallow whole; do not crush or chew the SR tablet
• Can be taken with or without food

Strict adherence to prescribed dosage is recommended.

Side Effects

Doxofyl SR is generally well tolerated, but some side effects may occur:

• Nausea or vomiting
• Headache
• Insomnia or restlessness
• Gastric irritation
• Rarely, palpitations or allergic reactions

Consult a healthcare provider if adverse effects persist or worsen.

Contraindications

• Hypersensitivity to Doxophylline or xanthine derivatives
• Severe cardiac arrhythmias (use with caution)

Precautions & Warnings

• Not suitable for acute asthma attacks requiring emergency relief
• Use cautiously in patients with heart disease, hypertension, or liver impairment
• Avoid excessive caffeine intake during treatment
• Long-term therapy may require periodic monitoring

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Use in Pregnancy & Lactation

The safety of Doxophylline during pregnancy and lactation is not fully established. It should be used only if clearly necessary and under medical supervision.

Storage

• Store below 30°C
• Keep in a dry place, protected from light
• Do not crush or break SR tablets
• Keep out of reach of children.