CoralCal-Kit Tablet 150 mg + 600 mg + 400 IU is a combination supplement and therapeutic tablet designed to support bone health, prevent fractures, and improve skeletal strength in patients with osteoporosis or at risk of bone loss.

This formulation combines:

• Ibandronic Acid 150 mg – a potent bisphosphonate that inhibits bone resorption

• Coral Calcium 600 mg – a natural, bioavailable source of calcium

• Vitamin D3 400 IU – essential for calcium absorption and bone mineralization

The synergistic combination of these ingredients helps reduce bone turnover, increase bone mineral density (BMD), and prevent fractures, particularly in postmenopausal women and adults with osteoporosis. CoralCal-Kit is indicated for both treatment and maintenance of bone health.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Class

• Bisphosphonate preparations

• Nutritional supplements for bone health

Pharmacology

• Ibandronic Acid: A nitrogen-containing bisphosphonate that selectively binds to bone hydroxyapatite. It inhibits osteoclast activity, reducing bone resorption and turnover, leading to progressive bone mass gain. It does not interfere with osteoclast recruitment and does not directly affect bone formation.

• Coral Calcium: Provides bioavailable calcium, essential for bone formation, maintenance, and strength. Adequate calcium intake helps prevent osteopenia and osteoporosis.

• Vitamin D3 (Cholecalciferol): Enhances intestinal absorption of calcium, regulates serum calcium and phosphate levels, and contributes to bone mineralization.

Together, these components slow the progression of osteoporosis, improve bone density, and reduce the risk of fractures.

Indications

CoralCal-Kit Tablet is indicated for:

• Treatment of postmenopausal osteoporosis

• Reduction of fracture risk in individuals with low bone mass

• Prevention of bone loss in adults at risk of osteoporosis

• Supplementation in patients with insufficient dietary calcium or vitamin D

Dosage and Administration

• Recommended dose: One tablet once monthly, or as prescribed by the physician

• Take on an empty stomach with a full glass of plain water (180–240 ml)

• Remain upright for at least 60 minutes after taking the tablet to prevent esophageal irritation

• Do not chew, crush, or suck the tablet

• If a monthly dose is missed and the next scheduled dose is more than 7 days away, take the missed dose the following morning and return to the regular schedule. If less than 7 days remain, wait for the next scheduled dose.

Drug Interactions

• Calcium and antacids may reduce ibandronic acid absorption; take at least 60 minutes apart

• No significant interactions with H2 antagonists, proton pump inhibitors, metformin, or bisphosphonates

• Caution with anticoagulants and other medications affecting calcium metabolism

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Contraindications

• Hypersensitivity to ibandronic acid, coral calcium, vitamin D3, or excipients

• Uncorrected hypocalcemia

• Severe renal impairment or inability to sit/stand upright for at least 60 minutes

• Esophageal abnormalities (e.g., stricture, achalasia)

Side Effects

• Common: Dyspepsia, nausea, abdominal pain, constipation, diarrhea, headache

• Rare: Esophagitis, esophageal ulcers, osteonecrosis of the jaw (ONJ)

• Patients should report difficulty swallowing, retrosternal pain, or new/worsening heartburn

Pregnancy and Lactation

• Not recommended during pregnancy or lactation

• Use only if benefits outweigh risks and under strict medical supervision

Precautions and Warnings

• Correct hypocalcemia or vitamin D deficiency before therapy

• Ensure adequate calcium and vitamin D intake

• Monitor for upper GI adverse events

• Maintain hydration and upright posture after administration

Storage Conditions

• Store in a cool, dry place below 30°C

• Protect from light and moisture

• Keep out of reach of children

Mode of Action

• Ibandronic acid inhibits osteoclast-mediated bone resorption

• Coral calcium supplies essential mineral for bone structure

• Vitamin D3 enhances calcium absorption and supports bone mineralization

• Combined, they improve bone density, reduce fracture risk, and maintain skeletal health.