DDR Capsule 60 mg contains Dexlansoprazole, a potent proton pump inhibitor (PPI) used for the treatment of acid-related gastrointestinal disorders. It is specifically formulated for patients who require higher acid suppression, such as those with severe or erosive gastroesophageal reflux disease (GERD). Dexlansoprazole works by blocking the proton pumps in the stomach lining, thereby reducing gastric acid secretion and promoting healing of esophageal damage. The dual delayed-release (DDR) technology in this formulation allows for prolonged and consistent acid suppression over 24 hours, enabling once-daily dosing and improved patient compliance.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Dexlansoprazole 60 mg

• Dosage Form: Oral capsule

• Route of Administration: Oral

Mechanism of Action

Dexlansoprazole is a selective H+/K+ ATPase inhibitor that targets gastric parietal cells:

• Blocks the final step of acid secretion, reducing basal and stimulated gastric acid output

• Dual delayed-release formulation ensures gradual and sustained release of the active ingredient, maintaining consistent acid suppression throughout the day

• Heals erosive esophagitis by protecting the esophageal lining from acid damage

• Reduces symptoms of heartburn, acid regurgitation, and other GERD-related discomforts

This targeted action allows effective management of severe acid reflux with minimal systemic exposure.

Indications

DDR Capsule 60 mg is indicated for:

• Severe gastroesophageal reflux disease (GERD) with erosive esophagitis

• Maintenance therapy in patients with healed erosive esophagitis to prevent relapse

• Management of frequent heartburn in adults where standard doses are insufficient

• Conditions requiring long-term gastric acid suppression, such as Zollinger-Ellison syndrome (under medical supervision)

Dosage and Administration

• Recommended dose: 60 mg once daily, taken orally, with or without food

• Swallow the capsule whole; do not crush, chew, or split to preserve the extended-release properties

• Duration of treatment depends on clinical response; typical therapy ranges from 8–12 weeks for healing of erosive esophagitis

• For long-term maintenance, follow physician guidance regarding dose and duration

• Consistent daily intake is essential for effective acid control

Contraindications

DDR Capsule 60 mg should not be used in:

• Patients with hypersensitivity to Dexlansoprazole or other PPIs

• Severe hepatic impairment without medical supervision

• Individuals with known hypersensitivity to any component of the capsule

Precautions and Warnings

• Use caution in patients with liver dysfunction

• Long-term use may lead to vitamin B12 deficiency, low magnesium levels, or increased risk of bone fractures

• May interact with drugs requiring stomach acidity for absorption (e.g., ketoconazole, atazanavir)

• Seek medical advice if persistent diarrhea, abdominal pain, or gastrointestinal bleeding occurs

• Not intended for immediate relief of occasional heartburn

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

DDR Capsule 60 mg is generally well tolerated. Common side effects may include:

• Headache

• Nausea, vomiting, or diarrhea

• Abdominal discomfort or bloating

• Rare but serious: allergic reactions, liver enzyme elevation, or severe dermatological reactions

Storage

Store in a cool, dry place below 30°C. Protect from moisture and light. Keep out of reach of children.

Conclusion

DDR Capsule 60 mg provides potent and prolonged acid suppression for patients with severe GERD and erosive esophagitis. Its dual delayed-release formulation allows for once-daily dosing, effective healing of esophageal erosions, and long-term management of acid-related disorders. When combined with lifestyle modifications and medical supervision, DDR Capsule 60 mg is a safe, reliable, and convenient option for sustained relief from acid reflux and associated complications.