Depomed Tablet 16 mg contains Methylprednisolone 16 mg, a potent synthetic corticosteroid used for its anti-inflammatory, immunosuppressive, and anti-allergic properties. This oral tablet formulation is designed for systemic therapy in conditions that require moderate to high corticosteroid doses. Methylprednisolone is part of the glucocorticoid class of drugs, widely prescribed for controlling inflammation, suppressing overactive immune responses, and managing acute or chronic allergic reactions.

The active ingredient works by inhibiting the production of inflammatory mediators such as prostaglandins, leukotrienes, and cytokines. It reduces migration of white blood cells to inflamed tissues, decreases capillary permeability, and modulates immune system activity. These combined actions relieve pain, swelling, redness, and tissue damage, making it effective for a wide range of medical conditions.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Depomed Tablet 16 mg is indicated for the management of conditions that require moderate to high-dose corticosteroid therapy, including:

• Rheumatoid arthritis and other severe inflammatory joint disorders

• Osteoarthritis flare-ups

• Connective tissue and autoimmune diseases such as systemic lupus erythematosus

• Severe allergic reactions including drug-induced hypersensitivity and angioedema

• Asthma exacerbations and chronic obstructive pulmonary disease (COPD) flare-ups

• Dermatological conditions such as severe psoriasis, eczema, and dermatitis

• Inflammatory bowel disease including Crohn’s disease and ulcerative colitis

• Hematologic and endocrine disorders requiring systemic corticosteroid therapy

The 16 mg dosage allows for effective control of symptoms while providing flexibility for dose tapering under medical supervision.

Dosage and Administration

The dosage of Depomed Tablet 16 mg must be individualized by a healthcare professional according to the patient’s condition, severity of symptoms, and response to therapy.

• Typically administered orally once daily or divided into multiple doses as prescribed

• Can be taken with food to reduce gastrointestinal discomfort

• Follow the prescribed schedule strictly; do not adjust the dose without consulting a physician

• Gradual tapering is recommended for prolonged therapy to prevent adrenal insufficiency

Precautions

• Contraindicated in patients with hypersensitivity to corticosteroids

• Use cautiously in patients with diabetes, hypertension, glaucoma, osteoporosis, or peptic ulcer disease

• May suppress the immune system, increasing susceptibility to infections

• Avoid live vaccines during corticosteroid therapy

• Inform the physician of ongoing infections, chronic illnesses, or recent vaccinations

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects may include:

• Fluid retention and weight gain

• Elevated blood sugar levels

• Increased appetite

• Mood changes, irritability, or insomnia

• Stomach discomfort

Serious adverse effects are more likely with prolonged or high-dose therapy. Immediate medical attention is required if severe allergic reactions, vision changes, unusual bruising, or signs of infection occur.

Storage

• Store below 30°C in a dry place

• Protect from light and moisture

• Keep out of reach of children

Depomed Tablet 16 mg provides potent, effective corticosteroid therapy for managing moderate to severe inflammatory, allergic, and autoimmune conditions when used under proper medical supervision.