Unipril Tablet 2.5 mg contains Ramipril, a widely used angiotensin-converting enzyme (ACE) inhibitor. It is primarily indicated for the management of hypertension (high blood pressure) and heart failure, as well as for reducing cardiovascular risk in patients at high risk of heart attack or stroke.

Ramipril works by relaxing blood vessels, lowering blood pressure, and improving blood flow, which reduces the workload on the heart and protects vital organs such as the kidneys. The 2.5 mg strength offers a starting dose suitable for patients initiating therapy or requiring dose titration.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Ramipril 2.5 mg

The formulation also includes standard excipients that aid tablet stability and absorption.

Mechanism of Action

Ramipril is an ACE inhibitor, which works by:

• Blocking the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor

• Relaxing blood vessels and reducing peripheral vascular resistance

• Lowering blood pressure, thereby decreasing the workload on the heart

• Reducing aldosterone secretion, which limits sodium and water retention

• Protecting kidney function, particularly in patients with diabetes or proteinuria

By these mechanisms, Ramipril not only controls blood pressure but also reduces the risk of cardiovascular events and slows the progression of kidney damage.

Indications

Unipril Tablet 2.5 mg is indicated for:

• Hypertension (high blood pressure) – alone or in combination with other antihypertensives

• Heart failure – to improve symptoms and reduce mortality

• Post-myocardial infarction – for cardiac remodeling and prevention of heart failure

• Prevention of cardiovascular events – in high-risk patients with diabetes, previous stroke, or coronary artery disease

• Chronic kidney disease – to slow progression of renal impairment

Dosage and Administration

• Adults: Starting dose is usually 2.5 mg once daily. The dose may be gradually increased based on blood pressure response and patient tolerance.

• Elderly or patients with kidney impairment: Dose adjustment may be necessary

• Tablets should be taken at the same time each day, preferably with or without food

• Regular monitoring of blood pressure, kidney function, and electrolytes is recommended

Precautions and Warnings

• Hypersensitivity: Contraindicated in patients with known allergy to ACE inhibitors

• Pregnancy: Should be avoided, especially in the second and third trimesters

• Kidney impairment: Dose adjustment may be required

• Hyperkalemia: Monitor serum potassium levels in at-risk patients

• Angioedema risk: Seek immediate medical attention if swelling of the face, lips, or throat occurs

• Avoid concomitant use with aliskiren in patients with diabetes or kidney impairment

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Side Effects

Unipril Tablet 2.5 mg is generally well tolerated. Possible side effects include:

• Dizziness or lightheadedness

• Persistent dry cough

• Headache

• Fatigue

• Rare: angioedema, hyperkalemia, or kidney function impairment

Patients should report any severe or persistent symptoms to their healthcare provider promptly.

Storage

Store below 30°C in a cool, dry place. Protect from moisture and light. Keep out of reach of children.

Conclusion

Unipril Tablet 2.5 mg (Ramipril) is a safe and effective ACE inhibitor for managing hypertension, heart failure, and cardiovascular risk. With its proven ability to lower blood pressure, improve heart function, and protect the kidneys, Unipril offers a reliable therapeutic option when used under medical supervision.