Diasulin N Injection 100 IU/ml contains Insulin Human (rDNA), an intermediate-acting insulin (NPH) designed to manage blood glucose levels in patients with type 1 or type 2 diabetes mellitus. Produced using recombinant DNA technology, this insulin provides predictable and reliable glycemic control. Diasulin N is primarily used to maintain basal insulin levels, helping to control fasting blood glucose and reduce the risk of long-term diabetes complications.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Insulin Human (rDNA, NPH)
• Strength: 100 IU/ml

Indications

Diasulin N Injection is indicated for:

• Type 1 diabetes mellitus requiring basal insulin therapy
• Type 2 diabetes mellitus when oral antidiabetic agents are insufficient
• Management of fasting hyperglycemia
• Patients needing intermediate-acting insulin coverage as part of a basal-bolus regimen

Mechanism of Action

NPH insulin provides intermediate-acting glucose control by slowly releasing insulin over 12–16 hours after subcutaneous injection. Insulin lowers blood glucose by:

• Promoting cellular uptake of glucose in muscle and fat tissues
• Inhibiting hepatic glucose production
• Supporting protein and lipid metabolism

This helps maintain stable fasting and basal blood glucose levels throughout the day.

Dosage and Administration

• Administer subcutaneously as prescribed by a healthcare professional
• Typically injected once or twice daily depending on individual glucose control requirements
• Rotate injection sites to prevent lipodystrophy
• Do not mix with other insulins unless directed by a physician
• Regular blood glucose monitoring is recommended to adjust dosage

Benefits

• Provides predictable intermediate-acting basal insulin coverage
• Supports stable fasting blood glucose control
• Can be used alone or in combination with rapid-acting insulin for basal-bolus therapy
• Recombinant DNA production ensures high purity and low risk of allergic reactions
• Reduces long-term risk of diabetes-related complications

Side Effects

Common side effects may include:

• Hypoglycemia (low blood sugar)
• Injection site reactions such as redness, swelling, or itching
• Mild weight gain

Rare side effects:

• Severe allergic reactions
• Lipodystrophy at repeated injection sites

Seek immediate medical attention if severe hypoglycemia or allergic reactions occur.

Precautions

• Monitor blood glucose regularly to avoid hypoglycemia or hyperglycemia
• Adjust dose during illness, stress, or changes in diet or activity
• Use cautiously in patients with kidney, liver, or cardiovascular conditions
• Carry a source of fast-acting sugar to manage hypoglycemia

Contraindications

• Hypersensitivity to Insulin Human or any component of the formulation
• Severe hypoglycemia

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

• May interact with oral antidiabetic drugs, corticosteroids, beta-blockers, diuretics, and other medications affecting blood glucose
• Inform your healthcare provider about all medications currently being taken

Storage

• Store refrigerated at 2–8°C; do not freeze
• Protect from heat and light
• Once opened, in-use vials can be stored at room temperature (below 30°C) for up to 28 days
• Keep out of reach of children.