Tamoxi Tablet 20 mg contains Tamoxifen Citrate, a selective estrogen receptor modulator (SERM) widely used in the treatment and prevention of hormone receptor-positive breast cancer. It works by blocking the effects of estrogen in breast tissue, helping to slow or stop the growth of estrogen-dependent cancer cells.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Tamoxifen Citrate 20 mg

Mechanism of Action

Tamoxifen binds to estrogen receptors in breast tissue and acts as an estrogen antagonist. By blocking estrogen from binding to its receptors, it reduces the stimulation of breast cancer cells that depend on estrogen for growth. In other tissues, such as bone and uterus, it may exhibit partial estrogen-like activity.

Indications

Tamoxi Tablet 20 mg is indicated for:

• Treatment of hormone receptor-positive breast cancer in women and men
• Adjuvant therapy after surgery, chemotherapy, or radiotherapy for breast cancer
• Reduction of risk of breast cancer recurrence
• Prevention of breast cancer in high-risk patients (as advised by a physician)

Dosage and Administration

• The dosage should be prescribed by an oncologist.
• Commonly taken once daily at the same time each day.
• Can be taken with or without food.
• Treatment duration may extend for several years depending on clinical condition.
• Regular follow-up and monitoring are essential during therapy.

Benefits

• Helps slow or stop the growth of hormone-sensitive breast cancer
• Reduces risk of cancer recurrence
• Effective long-term adjuvant therapy
• Oral once-daily dosing improves compliance
• Well-established treatment in breast cancer management

Side Effects

Common side effects may include:

• Hot flashes
• Nausea
• Fatigue
• Menstrual irregularities
• Mood changes
• Vaginal discharge or dryness

Serious but rare side effects may include blood clots, endometrial changes, stroke, or vision disturbances. Immediate medical attention is required if severe symptoms occur.

Precautions and Warnings

• Use only under oncologist supervision.
• Increased risk of blood clots; caution in patients with history of thromboembolic disorders.
• Regular gynecological monitoring is recommended in women.
• Not recommended during pregnancy due to risk of fetal harm.
• Use effective contraception during and after treatment as advised.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Tamoxi Tablet may interact with:

• Anticoagulants (e.g., warfarin)
• Certain antidepressants (SSRIs such as fluoxetine, paroxetine)
• Estrogen-containing medications
• CYP2D6 enzyme inhibitors (may reduce effectiveness)

Always inform your healthcare provider about all medications being used.

Storage

• Store below 30°C in a cool, dry place
• Protect from light and moisture
• Keep out of reach of children.