Dilapress Tablet 12.5 mg contains Carvedilol, a widely used cardiovascular medicine indicated for the management of hypertension and various heart-related disorders. Carvedilol is a non-selective beta-adrenergic blocker with additional alpha-1 blocking activity, providing effective blood pressure control along with cardioprotective benefits. Dilapress Tablet 12.5 mg is suitable for patients who require a higher maintenance dose for optimal therapeutic response.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Carvedilol 12.5 mg

Therapeutic Class

Beta-blocker with alpha-1 blocking activity
Antihypertensive and heart failure management agent

Pharmacology

Carvedilol exerts its therapeutic action by blocking beta-1, beta-2, and alpha-1 adrenergic receptors. Beta-1 receptor blockade leads to a reduction in heart rate and myocardial contractility, thereby decreasing cardiac workload and oxygen demand. Alpha-1 receptor blockade causes peripheral vasodilation, resulting in reduced systemic vascular resistance and lower blood pressure.

In addition to its receptor-blocking properties, carvedilol possesses antioxidant effects that help protect myocardial cells from oxidative stress. It improves left ventricular ejection fraction and reduces morbidity and mortality in patients with chronic heart failure. After oral administration, carvedilol is well absorbed and extensively metabolized in the liver.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Dilapress Tablet 12.5 mg is indicated for the treatment of:

• Hypertension

• Chronic stable angina pectoris

• Mild to severe chronic heart failure (as adjunct therapy)

• Left ventricular dysfunction following myocardial infarction

Consistent use helps reduce cardiovascular complications and improves long-term cardiac outcomes.

Dosage and Administration

• Hypertension: The usual dose is 12.5 mg once or twice daily, depending on patient response and clinical condition.

• Heart failure: Treatment is initiated at lower doses and gradually increased to 12.5 mg under strict medical supervision.

The tablet should be taken with food to minimize the risk of postural hypotension. Dose adjustments should be made by a healthcare professional.

Contraindications

Dilapress Tablet 12.5 mg is contraindicated in patients with:

• Bronchial asthma or severe obstructive airway disease

• Severe bradycardia

• Second or third-degree atrioventricular block

• Cardiogenic shock

• Severe hepatic impairment

• Known hypersensitivity to carvedilol

Precautions and Warnings

• Caution is required in diabetic patients as carvedilol may mask hypoglycemic symptoms.

• Abrupt discontinuation should be avoided; doses must be tapered gradually.

• Use with caution in patients with renal impairment, peripheral vascular disease, or thyroid disorders.

• Regular monitoring of blood pressure and heart rate is recommended.

Side Effects

Dilapress Tablet is generally well tolerated. Reported side effects may include:

• Dizziness

• Fatigue

• Hypotension

• Bradycardia

• Gastrointestinal disturbances

Most adverse effects are mild and transient.

Use in Special Populations

• Pregnancy: Should be used only if clearly indicated and prescribed by a physician.

• Lactation: Use with caution, as carvedilol may pass into breast milk.

• Elderly patients: Dose titration should be done carefully.

Storage

Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.