Dinakion Injection 10 mg/ml contains Phytomenadione, commonly known as Vitamin K1, a fat-soluble vitamin essential for blood coagulation. Administered via intramuscular (IM) or intravenous (IV) injection, Dinakion is used to prevent or treat Vitamin K deficiency, particularly in situations where rapid correction of coagulation is required. This injectable formulation is especially valuable in patients who cannot take oral vitamin K or have impaired absorption due to gastrointestinal conditions.

Phytomenadione is vital for the synthesis of several clotting factors in the liver, including Factors II (prothrombin), VII, IX, and X. These proteins play a crucial role in the blood coagulation cascade, ensuring proper clot formation and reducing the risk of excessive bleeding. Beyond coagulation, Vitamin K also contributes to bone health by regulating calcium-binding proteins in bones and soft tissues.

Dinakion Injection 10 mg/ml is commonly used in hospital settings to provide rapid correction of bleeding tendencies due to deficiency, anticoagulant overdose, or certain medical conditions.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Dinakion Injection 10 mg/ml is indicated for:

• Prevention and treatment of Vitamin K deficiency

• Correction of hypoprothrombinemia caused by inadequate dietary intake, malabsorption, or liver disease

• Management of excessive bleeding in patients on anticoagulants (e.g., warfarin)

• Prevention of Vitamin K deficiency bleeding (VKDB) in newborns, especially preterm infants

• Supportive therapy in patients with cholestasis, biliary obstruction, or other conditions affecting fat-soluble vitamin absorption

It is particularly useful in emergencies where rapid normalization of coagulation is necessary.

Dosage and Administration

The dosage and route of administration depend on patient age, clinical condition, and urgency:

• Adults: Typical doses range from 5–10 mg via IV or IM injection, as prescribed by the physician.

• Children and Infants: Dose is weight-based and should be determined by a healthcare professional.

• Neonates: Usually administered as a single prophylactic dose to prevent VKDB.

Administration Notes:

• IV administration should be performed slowly to reduce the risk of adverse reactions.

• IM injections should be given carefully, especially in neonates and patients with clotting disorders.

• The injection should be prepared and administered under strict aseptic conditions.

Precautions

• Contraindicated in patients with known hypersensitivity to Phytomenadione or any component of the injection.

• Use cautiously in patients with severe liver or kidney impairment.

• Monitor coagulation parameters when correcting over-anticoagulation.

• IV administration should be slow; rapid injection may cause hypotension or allergic reactions.

• Not intended for long-term use without medical supervision.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Dinakion Injection is generally well tolerated. Rare side effects may include:

• Mild pain or swelling at the injection site (IM)

• Redness or rash

• Hypersensitivity reactions, including anaphylaxis (rare)

• Dizziness or headache

• Flushing or warmth during IV infusion

Serious reactions are extremely uncommon when administered correctly under medical supervision.

Storage

Store below 25°C in a cool, dry place, protected from light. Keep out of reach of children. Do not use the injection if the solution is discolored or contains particles.

Dinakion Injection 10 mg/ml provides rapid and effective supplementation of Vitamin K1, ensuring proper blood clotting and supporting the prevention and treatment of deficiency-related bleeding under professional medical guidance.