Disartan Tablet 5 mg+20 mg is a combination antihypertensive medication containing Amlodipine Besilate 5 mg and Olmesartan Medoxomil 20 mg, formulated to provide effective blood pressure control in patients with hypertension. By combining two complementary mechanisms of action, this tablet offers enhanced efficacy and convenience for patients who require combination therapy.

Amlodipine Besilate is a calcium channel blocker that works by relaxing the smooth muscles of blood vessels, thereby reducing vascular resistance and lowering blood pressure. It also improves blood flow to the heart, which may help reduce chest pain (angina) in patients with coronary artery disease.

Olmesartan Medoxomil is an angiotensin II receptor blocker (ARB) that inhibits the action of angiotensin II, a hormone that causes blood vessels to constrict and raises blood pressure. By blocking this hormone, Olmesartan helps dilate blood vessels, reduce peripheral resistance, and maintain better cardiac and renal function.

Together, these two agents provide a synergistic effect, improving blood pressure control more effectively than monotherapy while reducing the risk of side effects associated with higher doses of individual drugs.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Disartan Tablet 5 mg+20 mg is indicated for:

• Treatment of hypertension in adults when monotherapy with a single antihypertensive is insufficient

• Reduction of cardiovascular risk in patients with high blood pressure and associated risk factors

• Management of patients requiring dual therapy to achieve target blood pressure

This combination is suitable for patients who require both vascular relaxation and renin-angiotensin system inhibition for optimal blood pressure control.

Dosage and Administration

• Adults: One tablet daily, preferably at the same time each day, with or without food, as prescribed by a physician.

• Do not exceed the prescribed dose without medical supervision.

• Consistent daily intake is important for maintaining stable blood pressure and achieving maximum therapeutic benefit.

Patients should continue lifestyle measures such as reducing salt intake, maintaining a healthy weight, exercising regularly, and avoiding excessive alcohol consumption, as these enhance the effectiveness of antihypertensive therapy.

Precautions

• Contraindicated in patients with known hypersensitivity to Amlodipine, Olmesartan, or any component of the tablet.

• Caution is advised in patients with severe liver or kidney impairment, aortic stenosis, or heart failure.

• May cause dizziness or hypotension, particularly during the initial days of treatment; patients should avoid driving or operating machinery until they know how the medication affects them.

• Pregnant or breastfeeding women should use only under strict medical supervision, as Olmesartan may harm the fetus.

• Regular monitoring of blood pressure, kidney function, and electrolytes is recommended during treatment.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Disartan Tablet is generally well tolerated. Common side effects may include:

• Dizziness, headache, or fatigue

• Flushing or swelling of the ankles (peripheral edema)

• Gastrointestinal disturbances, such as nausea

• Rarely, hypotension, palpitations, or allergic reactions

Serious adverse effects are uncommon but may include significant hypotension, kidney dysfunction, or hyperkalemia. Patients should report any unusual symptoms promptly.

Storage

Store below 30°C in a cool, dry place, away from light and moisture. Keep out of reach of children.

Disartan Tablet 5 mg+20 mg provides effective dual-action blood pressure control, combining calcium channel blockade and angiotensin II receptor antagonism, helping reduce cardiovascular risk and maintain optimal hypertension management under professional supervision.