Doltro Tablet 10 mg contains Ketorolac Tromethamine 10 mg, a potent non-steroidal anti-inflammatory drug (NSAID) used for the short-term management of moderate pain. Ketorolac provides effective analgesic and anti-inflammatory effects by inhibiting cyclooxygenase (COX) enzymes, which are responsible for the synthesis of prostaglandins that cause pain, inflammation, and fever.

Doltro is commonly prescribed for postoperative pain, musculoskeletal pain, dental pain, and other acute pain conditions where rapid relief is needed. It is suitable for adults requiring short-term therapy, typically not exceeding 5 days, due to the risk of adverse effects associated with prolonged NSAID use. This makes Doltro an effective option for managing pain without opioids, improving comfort and patient recovery after minor procedures or injuries.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Doltro Tablet 10 mg is indicated for:

• Relief of moderate to severe acute pain, including postoperative pain

• Management of musculoskeletal pain, such as sprains, strains, or back pain

• Treatment of dental pain after procedures or extractions

• Short-term therapy for conditions requiring analgesic and anti-inflammatory effects

Key Benefits

• Provides rapid and effective pain relief

• Reduces inflammation and associated swelling

• Non-opioid therapy, reducing risk of dependence

• Convenient oral tablet for easy administration

• Suitable for short-term use in adults to manage acute pain

Mechanism of Action

Ketorolac Tromethamine, the active ingredient in Doltro, is a non-selective inhibitor of cyclooxygenase (COX-1 and COX-2). By blocking these enzymes, Ketorolac decreases the production of prostaglandins, which are chemical mediators responsible for pain, inflammation, and fever.

• Analgesic effect: Reduces pain by limiting prostaglandin-mediated stimulation of nerve endings.

• Anti-inflammatory effect: Decreases inflammation by reducing prostaglandin-mediated vasodilation and fluid accumulation.

• Antipyretic effect: Lowers fever by acting on the hypothalamus to regulate body temperature.

This dual effect on pain and inflammation makes Doltro highly effective for managing acute pain conditions.

Dosage and Administration

• The typical adult dose is one tablet (10 mg) every 4–6 hours as needed for pain.

• Maximum recommended dose should not exceed 40 mg per day.

• Take the tablet orally with water, preferably after meals to reduce gastrointestinal irritation.

• Therapy should not exceed 5 days without medical supervision.

Precautions

• Use cautiously in patients with peptic ulcers, gastrointestinal bleeding, kidney or liver impairment, or cardiovascular disease.

• Avoid concomitant use with other NSAIDs or corticosteroids unless prescribed.

• Patients with a history of allergic reactions to NSAIDs should not take Doltro.

• Not recommended during late pregnancy due to potential effects on fetal circulation.

• Monitor for signs of gastrointestinal bleeding, kidney dysfunction, or allergic reactions during therapy.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Doltro Tablet 10 mg is generally well tolerated, but some side effects may occur:

• Gastrointestinal discomfort, nausea, or heartburn

• Dizziness or headache

• Rarely, gastrointestinal bleeding or kidney function impairment

• Allergic reactions such as rash or itching

Most side effects are mild and resolve with discontinuation or dose adjustment.

Storage

Store below 30°C in a cool, dry place, protected from light and moisture. Keep out of reach of children.