Dopair Tablet combines Levodopa 250 mg with Carbidopa 25 mg, a potent therapy for Parkinson’s disease and parkinsonian syndromes. Levodopa replenishes dopamine levels in the brain, improving motor function and reducing symptoms such as tremors, rigidity, and bradykinesia. Carbidopa inhibits the peripheral breakdown of Levodopa, increasing its availability in the central nervous system and reducing side effects like nausea and vomiting. This higher-strength formulation is suitable for patients requiring greater symptom control.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Levodopa 250 mg (dopamine precursor)
• Carbidopa 25 mg (peripheral dopa-decarboxylase inhibitor)

Indications

Dopair Tablet is indicated for:

• Parkinson’s disease (all stages)
• Parkinsonian syndromes caused by dopamine deficiency
• Relief of motor symptoms including tremor, rigidity, and slowness of movement

Mechanism of Action

• Levodopa: Crosses the blood-brain barrier and converts to dopamine in the brain, restoring deficient dopamine levels.
• Carbidopa: Prevents peripheral conversion of Levodopa to dopamine, allowing more Levodopa to reach the brain and reducing gastrointestinal and cardiovascular side effects.

Together, they provide effective symptom control and improved patient mobility.

Dosage and Administration

• Take orally as prescribed by a healthcare professional
• Typically administered 1–3 times daily depending on symptom severity and patient response
• Can be taken with or after meals to reduce gastrointestinal discomfort
• Do not abruptly discontinue therapy; adjust dosage only under medical supervision

Benefits

• Improves motor function and mobility in Parkinson’s patients
• Reduces tremors, rigidity, and bradykinesia
• Minimizes nausea and peripheral side effects with Carbidopa
• Enhances quality of life for patients with dopamine deficiency
• Convenient higher-strength tablet for patients needing greater symptom control

Side Effects

Common side effects:

• Nausea and vomiting
• Dizziness or lightheadedness
• Dyskinesia (involuntary movements)
• Orthostatic hypotension

Rare side effects:

• Hallucinations or confusion
• Cardiac arrhythmias
• Severe allergic reactions

Seek medical attention if severe or persistent side effects occur.

Precautions

• Monitor blood pressure regularly, especially in elderly patients
• Use with caution in patients with heart disease, psychiatric disorders, or liver/kidney impairment
• Avoid abrupt discontinuation to prevent worsening of Parkinsonian symptoms
• Inform your doctor about other medications, particularly MAO inhibitors and antihypertensives

Contraindications

• Hypersensitivity to Levodopa, Carbidopa, or any component of the formulation
• Narrow-angle glaucoma
• History of melanoma or suspicious skin lesions
• Concurrent use of non-selective MAO inhibitors

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

• May interact with MAO inhibitors, antipsychotics, antihypertensives, and iron supplements
• Always inform your healthcare provider of all medications currently being used

Storage

• Store in a cool, dry place below 30°C
• Protect from light and moisture
• Keep out of reach of children.