Dophylin Syrup 100 mg/5 ml contains Doxophylline, a xanthine derivative with potent bronchodilator properties. This oral liquid formulation is designed for children and adults who have difficulty swallowing tablets or capsules, ensuring accurate dosing and effective management of respiratory conditions. Dophylin Syrup provides relief from bronchospasm, wheezing, shortness of breath, and other symptoms associated with asthma and chronic obstructive pulmonary disease (COPD).

Doxophylline is structurally related to theophylline but is better tolerated, with a lower risk of central nervous system stimulation and cardiac side effects. It works by relaxing the smooth muscles of the airways, reducing inflammation, and improving oxygen flow, making it suitable for both acute and long-term management of obstructive airway diseases.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Doxophylline: 100 mg per 5 ml

Indications

Dophylin Syrup 100 mg/5 ml is indicated for:

• Bronchial asthma in children and adults (age-specific guidance required)

• Chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema

• Relief of wheezing, shortness of breath, and chest tightness

• Adjunct therapy for reversible airway obstruction

• Long-term management of chronic respiratory conditions to prevent exacerbations

• Patients requiring oral liquid formulations for ease of dosing

Mechanism of Action

Doxophylline acts via multiple mechanisms to improve respiratory function:

1. Bronchodilation: Relaxes smooth muscles in the bronchi and bronchioles, reducing airway resistance.

2. Anti-inflammatory effect: Decreases airway inflammation and mucus production.

3. Phosphodiesterase inhibition: Increases intracellular cyclic AMP (cAMP), promoting smooth muscle relaxation.

4. Minimal CNS and cardiac stimulation: Safer than theophylline for long-term use due to reduced excitatory effects.

These actions help manage both acute and chronic respiratory symptoms effectively, improving oxygenation and lung function.

Dosage and Administration

• Route: Oral

• Dosage: As prescribed by a registered physician

The usual dose depends on age, weight, and severity of the condition. Typically, 5–10 ml of syrup (equivalent to 100–200 mg Doxophylline) is given 1–2 times daily, preferably after meals to minimize gastric irritation. The syrup should be measured using a calibrated measuring spoon or oral syringe for accurate dosing.

Benefits of Dophylin Syrup 100 mg/5 ml

• Effective bronchodilation for asthma and COPD

• Improves lung function, oxygenation, and overall respiratory comfort

• Convenient oral liquid formulation suitable for children and adults

• Reduces frequency and severity of respiratory exacerbations

• Well-tolerated with minimal CNS and cardiac side effects

• Supports daily activity and quality of life in patients with chronic respiratory disease

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use only under medical supervision

• Caution in patients with heart disease, hypertension, liver or kidney impairment

• Monitor for side effects such as nausea, tremors, palpitations, or headache

• Avoid concomitant use with other xanthine derivatives unless prescribed

• Not recommended for pediatric patients under the age specified by a physician

• Long-term therapy requires regular medical follow-up

Storage Conditions

• Store below 30°C in a dry place

• Protect from light and moisture

• Keep out of reach of children

• Shake well before use

Pharmaceutical Category

Bronchodilator / Xanthine Derivative.