Nystat Plus Cream 1%+2% is a dual-action topical cream combining Chlorhexidine Hydrochloride 1% and Nystatin 2%, designed to treat a variety of fungal and bacterial skin infections. This combination provides both antifungal and antibacterial protection, making it ideal for conditions where mixed infections are present or at risk.

• Nystatin is an antifungal agent that targets yeast infections, particularly Candida species, by disrupting the fungal cell membrane.

• Chlorhexidine Hydrochloride is a broad-spectrum antibacterial agent that helps eliminate bacteria and prevent secondary infections.

Together, these active ingredients help relieve symptoms such as itching, redness, inflammation, and irritation, while promoting faster healing of affected skin areas.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Nystat Plus Cream is indicated for the topical treatment of fungal and bacterial skin infections, including:

• Candidiasis (yeast infections of the skin)

• Intertrigo (inflammation in skin folds due to fungal and bacterial growth)

• Minor mixed bacterial-fungal skin infections

• Diaper rash with secondary infections

• Athlete’s foot (Tinea pedis) and other superficial fungal infections where bacterial contamination is present

The cream is suitable for use on areas prone to moisture, friction, or irritation, where mixed infections are common.

Mechanism of Action

1. Nystatin (2%):

   • Binds to ergosterol in fungal cell membranes, creating pores.

   • Causes leakage of cellular contents, resulting in fungal cell death.

2. Chlorhexidine Hydrochloride (1%):

   • Disrupts bacterial cell membranes and precipitates cell proteins.

   • Provides a broad-spectrum antibacterial effect, preventing secondary infections.

The synergistic action of these two ingredients ensures comprehensive management of infections caused by both fungi and bacteria, accelerating recovery and reducing recurrence risk.

Dosage and Administration

• Clean and dry the affected area before application.

• Apply a thin layer of Nystat Plus Cream 1%+2% 2–3 times daily, or as directed by a healthcare professional.

• Gently rub the cream until fully absorbed.

• Continue application for the full prescribed duration, even if symptoms improve early, to prevent relapse.

Avoid contact with eyes, mucous membranes, or open wounds. Wash hands after each application.

Precautions and Warnings

• For external use only.

• Avoid using on large areas of damaged skin unless prescribed.

• Not recommended for patients with hypersensitivity to Nystatin, Chlorhexidine, or other cream components.

• Consult a physician if the condition persists, worsens, or spreads despite treatment.

• Use caution in infants or patients with sensitive skin.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Nystat Plus Cream is generally well-tolerated. Mild side effects may include:

• Redness or irritation at the application site

• Burning or stinging sensation

• Allergic reactions (rare)

Discontinue use and seek medical attention if severe irritation or rash develops.

Storage

Store below 30°C in a cool, dry place, away from direct sunlight. Keep the tube tightly closed and out of reach of children.

Nystat Plus Cream 1%+2% provides effective topical management of mixed fungal and bacterial skin infections, combining antifungal and antibacterial properties to relieve symptoms, prevent secondary infections, and promote faster healing.