Edvila-M Tablet 50 mg + 500 mg is a combination oral antidiabetic medicine that contains Vildagliptin and Metformin Hydrochloride. This formulation is used in the management of Type 2 Diabetes Mellitus, especially when a single drug does not provide adequate glycemic control.

The lower metformin strength (500 mg) is often preferred in patients who are starting therapy or those who cannot tolerate higher doses.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Vildagliptin 50 mg
• Metformin Hydrochloride 500 mg

For oral administration.

Mechanism of Action

This combination works through complementary mechanisms:

• Vildagliptin inhibits the DPP-4 enzyme, increasing levels of incretin hormones (GLP-1 and GIP), which stimulate insulin release and suppress glucagon
• Metformin reduces glucose production in the liver and improves insulin sensitivity in muscle and peripheral tissues
• Together, they control both fasting and post-meal blood glucose levels

Indications

Edvila-M Tablet is indicated for:

• Type 2 Diabetes Mellitus
• Patients inadequately controlled with diet, exercise, or single-drug therapy
• Combination therapy for improved glycemic control

Dosage and Administration

• Usually taken once or twice daily with meals to minimize gastrointestinal side effects
• Dose should be individualized based on patient condition
• Take regularly at the same time each day
• Follow physician’s instructions carefully

Benefits

Edvila-M Tablet provides several benefits:

• Effective dual control of blood sugar levels
• Reduces HbA1c significantly
• Low risk of hypoglycemia when used appropriately
• Improves insulin function and sensitivity
• Lower dose of metformin improves tolerability

Possible Side Effects

Common side effects include:

• Nausea
• Diarrhea
• Abdominal discomfort
• Headache

Serious but rare side effects:

• Lactic Acidosis
• Liver enzyme abnormalities
• Pancreatitis (rare)

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Monitor blood glucose, kidney, and liver function regularly
• Avoid in patients with severe kidney or liver impairment
• Limit alcohol intake to reduce risk of lactic acidosis
• Not suitable for Type 1 Diabetes
• Inform doctor about all other medications

Storage

Store in a cool, dry place below 30°C, protected from light and moisture. Keep out of reach of children.