Mircera Injection 75 µg/0.3 ml contains Methoxy Polyethylene Glycol-Epoetin Beta, a long-acting erythropoiesis-stimulating agent (ESA) used for the management of anemia associated with chronic kidney disease (CKD). It promotes the production of red blood cells in the bone marrow, helping to increase and maintain hemoglobin levels.

Anemia is a common complication in CKD patients due to reduced production of natural erythropoietin by the kidneys. Mircera provides continuous stimulation of erythropoietin receptors, offering sustained red blood cell production and allowing for extended dosing intervals compared to traditional ESAs.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Benefits

• Long-acting formulation
  Designed for extended activity, enabling less frequent injections.

• Effective hemoglobin control
  Helps achieve and maintain target hemoglobin levels.

• Reduced treatment burden
  Administered every two weeks or once monthly, depending on clinical needs.

• Suitable for dialysis and non-dialysis patients
  Effective in a wide range of CKD patients under medical supervision.

Indications

Mircera Injection 75 µg/0.3 ml is indicated for:

• Treatment of anemia associated with chronic kidney disease in adult patients.

• Maintenance of hemoglobin levels in CKD patients receiving dialysis or not on dialysis.

Therapy should be initiated and monitored by a qualified healthcare professional experienced in anemia management.

Dosage and Administration

• Administered by subcutaneous (SC) or intravenous (IV) injection.

• Dosage is individualized based on hemoglobin levels, body weight, and clinical response.

• Regular monitoring of hemoglobin is essential to guide dose adjustments.

• Iron status should be assessed and corrected as needed during therapy.

Do not shake the solution. Use only as prescribed by a healthcare provider.

Mechanism of Action

Methoxy Polyethylene Glycol-Epoetin Beta acts as a continuous erythropoietin receptor activator (CERA). It binds to erythropoietin receptors in the bone marrow, stimulating red blood cell production over an extended period, resulting in stable hemoglobin control.

Safety Information

Contraindications:

• Uncontrolled hypertension.

• Hypersensitivity to methoxy polyethylene glycol-epoetin beta or any component of the formulation.

Warnings and precautions:

• Monitor blood pressure regularly.

• Avoid excessive hemoglobin increases to reduce cardiovascular risk.

• Increased risk of thromboembolic events may occur if hemoglobin rises too rapidly.

• Regular laboratory monitoring is required during treatment.

Common side effects may include hypertension, headache, injection site reactions, and vascular access thrombosis in dialysis patients.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

Store in a refrigerator at 2°C to 8°C. Do not freeze. Keep in the original packaging to protect from light. Keep out of reach of children.