Edvila-M Tablet 50 mg + 850 mg is a combination antidiabetic medicine containing Vildagliptin and Metformin Hydrochloride. This dual therapy is designed to provide better blood sugar control in patients with Type 2 Diabetes Mellitus when a single medication is not sufficient.

The combination works through complementary mechanisms to improve insulin secretion and reduce excess glucose production.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Vildagliptin 50 mg
• Metformin Hydrochloride 850 mg

It is intended for oral administration.

Mechanism of Action

This combination provides synergistic glucose control:

• Vildagliptin inhibits the DPP-4 enzyme, increasing incretin hormones (GLP-1 and GIP), which enhance insulin secretion and reduce glucagon release
• Metformin decreases hepatic glucose production and improves insulin sensitivity in peripheral tissues
• Together, they help regulate both fasting and postprandial blood glucose levels

Indications

Edvila-M Tablet is indicated for:

• Type 2 Diabetes Mellitus
• Patients not adequately controlled with metformin or vildagliptin alone
• Combination therapy in patients requiring dual oral antidiabetic treatment

Dosage and Administration

• Usually taken once or twice daily with meals to reduce gastrointestinal side effects
• Dosage depends on patient response and prior therapy
• Should be taken regularly at the same time each day
• Follow physician’s instructions strictly

Benefits

Edvila-M Tablet offers multiple benefits:

• Improved blood sugar control through dual mechanism
• Targets both insulin secretion and insulin resistance
• Helps reduce HbA1c levels effectively
• Lower risk of hypoglycemia compared to some other therapies
• Convenient fixed-dose combination improves adherence

Possible Side Effects

Common side effects include:

• Nausea
• Diarrhea
• Abdominal discomfort
• Headache

Serious but rare side effects:

• Lactic Acidosis (rare but potentially fatal)
• Liver function abnormalities
• Pancreatitis (rare)

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Monitor blood glucose and kidney function regularly
• Avoid in patients with severe kidney or liver impairment
• Use cautiously in elderly patients
• Avoid excessive alcohol intake, as it increases risk of lactic acidosis
• Not recommended for Type 1 Diabetes
• Inform doctor about all concurrent medications

Storage

Store in a cool, dry place below 30°C, protected from moisture and light. Keep out of reach of children.