Egolix Tablet 150 mg contains Elagolix Sodium, an oral gonadotropin-releasing hormone (GnRH) receptor antagonist. It is primarily indicated for the management of moderate to severe pain associated with endometriosis in women of reproductive age. Egolix provides effective relief from endometriosis-related pelvic pain, dysmenorrhea, and non-menstrual pelvic pain by modulating hormone levels without the need for injectable therapy, offering a convenient oral option.

Elagolix works by suppressing the release of gonadotropins, which in turn decreases estrogen production. Reduced estrogen levels help shrink endometriotic lesions and alleviate symptoms of endometriosis while allowing for dose-dependent modulation of hormone suppression, which minimizes side effects compared to full estrogen suppression seen with traditional GnRH agonists.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Elagolix Sodium: 150 mg per tablet

Indications

Egolix Tablet 150 mg is indicated for:

• Moderate to severe pain associated with endometriosis, including dysmenorrhea and non-menstrual pelvic pain

• Management of endometriosis-related dyspareunia (pain during intercourse)

• Short-term treatment of endometriosis in women who do not respond adequately to non-hormonal therapy

• Option for women seeking oral therapy over injectable hormonal treatments

Mechanism of Action

Egolix (Elagolix Sodium) functions as a GnRH receptor antagonist in the hypothalamus and pituitary gland:

1. GnRH receptor blockade: Prevents the binding of natural GnRH to its receptors.

2. Reduced gonadotropin secretion: Decreases luteinizing hormone (LH) and follicle-stimulating hormone (FSH) release.

3. Lowered estrogen levels: Reduces estrogen-dependent endometrial tissue growth and inflammation.

4. Symptom relief: Decreases endometriosis-associated pelvic pain and dysmenorrhea.

Unlike GnRH agonists, Egolix provides immediate suppression of hormone levels without an initial flare, improving tolerability and offering flexible dosing based on symptom severity.

Dosage and Administration

• Route: Oral

• Dosage: As prescribed by a registered physician

The recommended dose for moderate to severe endometriosis pain is 150 mg once daily. Tablets should be taken with or without food, preferably at the same time each day to maintain steady drug levels. Therapy duration is generally short-term (up to 24 weeks), depending on symptom severity and physician guidance. Regular follow-up is recommended to monitor bone mineral density and overall hormonal balance, especially with extended therapy.

Benefits of Egolix Tablet 150 mg

• Provides effective relief from endometriosis-related pain

• Convenient once-daily oral administration

• Immediate suppression of estrogen without initial hormone flare

• Reduces dysmenorrhea, non-menstrual pelvic pain, and dyspareunia

• Avoids injections, making therapy more convenient and patient-friendly

• Supports improved quality of life and daily functioning for women with endometriosis

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use only under medical supervision

• Contraindicated in pregnancy, known osteoporosis, or hypersensitivity to Elagolix

• Monitor for bone mineral density changes, especially in long-term therapy

• May cause hot flashes, headache, mood changes, or irregular bleeding

• Not recommended for women planning pregnancy during treatment

• Avoid abrupt discontinuation without physician guidance

Storage Conditions

• Store below 30°C in a dry place

• Protect from light and moisture

• Keep out of reach of children

Pharmaceutical Category

GnRH Receptor Antagonist / Endometriosis Therapy / Hormonal Modulator.