Elazol Tablet 50 mg contains Voriconazole, a broad-spectrum antifungal agent from the triazole class. It is primarily used to treat serious fungal infections in patients who require precise dosing or step-down therapy from intravenous antifungals. Voriconazole is effective against invasive aspergillosis, candidiasis, and other systemic fungal infections.

Voriconazole works by inhibiting ergosterol synthesis, a vital component of fungal cell membranes. This disruption weakens the fungal cell wall, leading to cell death and resolution of the infection.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Voriconazole 50 mg

Mechanism of Action

Voriconazole acts through:

• Inhibition of lanosterol 14α-demethylase, a fungal cytochrome P450 enzyme

• Preventing the production of ergosterol, crucial for cell membrane integrity

• Disrupting fungal cell membranes, resulting in fungal cell death

• Providing broad-spectrum antifungal activity against yeasts and molds

Indications

Elazol Tablet 50 mg is indicated for:

• Step-down or maintenance therapy in systemic fungal infections

• Invasive aspergillosis

• Serious Candida infections, including candidemia

• Fusarium and Scedosporium infections

• Use in immunocompromised patients requiring oral antifungal therapy

Dosage and Administration

• The usual dose for adults is 50 mg orally every 12 hours, or as prescribed by a physician

• Take on an empty stomach to improve absorption

• Duration depends on infection type, severity, and response to therapy

• Regular monitoring of liver function and blood levels may be required during long-term therapy

Precautions

• Use with caution in patients with hepatic or renal impairment

• Avoid combining with drugs that strongly influence CYP450 enzymes

• Monitor for visual disturbances, liver toxicity, and skin reactions

• Not recommended during pregnancy or breastfeeding unless prescribed by a doctor

• Inform your healthcare provider of all concurrent medications

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects may include:

• Nausea, vomiting, or diarrhea

• Visual disturbances such as blurred vision or altered color perception

• Headache

• Skin rash or mild liver enzyme elevation

Rare but serious side effects:

• Severe liver toxicity

• Serious allergic reactions

• Cardiac arrhythmias in predisposed individuals

Storage

• Store below 25°C in a cool, dry place

• Protect from light and moisture

• Keep out of reach of children

Elazol Tablet 50 mg is a safe and effective oral antifungal for maintenance therapy or step-down treatment, providing broad-spectrum antifungal activity under proper medical supervision.