Empagliflozin is a sodium-glucose co-transporter 2 (SGLT2) inhibitor that lowers blood glucose by reducing renal glucose reabsorption in the proximal tubules of the kidneys. This results in increased urinary excretion of glucose, thereby decreasing plasma glucose levels independently of insulin action. Empagliflozin also supports modest weight loss and blood pressure reduction and has demonstrated cardiovascular and kidney protective effects in patients with type 2 diabetes.

Linagliptin (5 mg)
Linagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that enhances the activity of incretin hormones, which increase insulin secretion and reduce glucagon release in a glucose-dependent manner. This helps improve both fasting and postprandial blood glucose levels with a low risk of hypoglycemia. Linagliptin does not require dose adjustment in renal impairment, making it suitable for a wide range of patients.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Empalina Tablet 25 mg+5 mg is indicated for:

• Treatment of type 2 diabetes mellitus in adults

• Patients inadequately controlled with monotherapy or lower-dose combination therapy

• Adjunct to diet and exercise for improved glycemic control

• Patients requiring stronger SGLT2 inhibition for optimal glucose lowering

Key Benefits

• Dual-action therapy targeting different pathways of glucose regulation

• Enhanced glycemic control with higher-strength empagliflozin

• Low risk of hypoglycemia when used without insulin or sulfonylureas

• Supports weight management and blood pressure reduction

• Provides proven cardiovascular and renal protective benefits

• Convenient once-daily oral dosing improves compliance

Dosage and Administration

The usual recommended dose is one tablet once daily, taken orally with or without food, or as prescribed by a healthcare professional. Dose selection should be based on individual patient needs, treatment response, and renal function. Regular monitoring of blood glucose and renal parameters is recommended during therapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Not indicated for type 1 diabetes mellitus or diabetic ketoacidosis

• Use with caution in patients with severe renal impairment or volume depletion

• Ensure adequate hydration to reduce the risk of hypotension

• Monitor for signs of urinary tract and genital infections

• Use during pregnancy and breastfeeding only under medical supervision

Possible Side Effects

Commonly reported side effects include increased urination, urinary tract infections, genital fungal infections, headache, and nasopharyngitis. Hypoglycemia is uncommon unless combined with insulin or insulin secretagogues. Most side effects are mild to moderate and manageable.

Storage

Store below 30°C in a cool, dry place. Protect from moisture and direct sunlight. Keep out of reach of children.