Erenzo Tablet 20 mg contains Roxadustat, an innovative oral medication designed to treat anemia associated with chronic kidney disease (CKD) in both dialysis and non-dialysis patients. Roxadustat belongs to a class of drugs called hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs). It works by stimulating the body’s natural production of erythropoietin and enhancing iron utilization, helping restore hemoglobin levels and reduce symptoms of anemia such as fatigue, weakness, and shortness of breath.

Anemia is a common complication in patients with CKD, often resulting from reduced erythropoietin production by the kidneys. Untreated anemia can significantly affect quality of life, causing lethargy, impaired physical performance, and increased cardiovascular risk. Erenzo Tablet 20 mg offers a convenient, orally administered therapy that addresses the underlying mechanisms of CKD-related anemia while supporting effective red blood cell production.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Features and Benefits

Active Ingredient:

• Roxadustat 20 mg per tablet

Effective Anemia Management:

• Stimulates endogenous erythropoietin production

• Enhances iron absorption and utilization

• Restores hemoglobin levels and improves oxygen delivery

Convenient Oral Therapy:

• Oral tablet suitable for both dialysis and non-dialysis CKD patients

• Eliminates the need for injections required by traditional erythropoiesis-stimulating agents

• Supports better patient adherence and long-term treatment

Improved Quality of Life:

• Reduces fatigue, weakness, and shortness of breath

• Supports physical performance and daily activity

• May lower the need for blood transfusions

How It Works

Roxadustat acts as a hypoxia-inducible factor (HIF) stabilizer, mimicking the body’s natural response to low oxygen levels. HIF activation triggers the production of erythropoietin in the kidneys and liver, stimulating red blood cell production in the bone marrow. Roxadustat also improves iron availability by regulating hepcidin, a hormone that controls iron metabolism, allowing the body to effectively use stored iron for hemoglobin synthesis.

By addressing both erythropoietin deficiency and iron utilization, Erenzo provides a comprehensive approach to managing anemia in CKD patients.

Indications

Erenzo Tablet 20 mg is indicated for:

• Treatment of anemia in adult patients with chronic kidney disease, including those on dialysis

• Anemia management in non-dialysis CKD patients to improve hemoglobin levels

• Patients who require an oral alternative to injectable erythropoiesis-stimulating agents

Dosage and Administration

• Take the tablet orally as directed by your healthcare provider.

• Typically administered three times per week or according to individualized dosing plans.

• Swallow the tablet with water; it can be taken with or without food.

• Regular monitoring of hemoglobin, iron levels, and other laboratory parameters is recommended to ensure safe and effective therapy.

Do not adjust the dose or frequency without consulting your physician.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Safety Information

• Inform your doctor if you have a history of cardiovascular disease, hypertension, liver disease, or clotting disorders.

• Common side effects may include headache, nausea, diarrhea, and high blood pressure.

• Serious adverse events, although rare, may include thromboembolic events, heart failure, or severe hypertension. Seek immediate medical attention if severe symptoms occur.

• Use caution in patients with a history of stroke or myocardial infarction.

Storage Instructions

• Store below 30°C in a cool, dry place.

• Protect from moisture, light, and heat.

• Keep out of reach of children.

Erenzo Tablet 20 mg offers a safe and effective oral therapy for CKD-related anemia, helping patients achieve better hemoglobin levels, improved oxygen delivery, and enhanced quality of life. Its dual mechanism of stimulating erythropoietin and improving iron utilization provides a modern, convenient alternative to injectable treatments.