Evania M Tablet 5 mg + 500 mg is a combination oral antidiabetic medicine that contains Empagliflozin and Metformin Hydrochloride. It is used in the management of type 2 diabetes mellitus, particularly in patients who require dual therapy to achieve better glycemic control.

This lower-dose combination is often suitable for patients who are newly started on combination therapy or who require gradual dose titration.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Empagliflozin 5 mg
• Metformin Hydrochloride 500 mg

For oral administration.

Mechanism of Action

Evania M works through two complementary pathways:

Empagliflozin (SGLT2 inhibitor)

• Blocks glucose reabsorption in the kidneys
• Promotes excretion of excess glucose through urine
• Helps reduce blood sugar independently of insulin

Metformin (Biguanide)

• Reduces glucose production in the liver
• Improves insulin sensitivity in peripheral tissues
• Decreases intestinal glucose absorption

Together, these actions help control both fasting and post-meal blood glucose levels.

Indications

Evania M Tablet is indicated for:

• Type 2 Diabetes Mellitus
• Patients not adequately controlled with diet and exercise alone
• As combination therapy when single agents are insufficient

Dosage and Administration

• Usually taken once or twice daily with meals
• Taking with food helps reduce gastrointestinal side effects
• Dosage should be individualized by a physician
• Swallow whole with water; do not crush or chew
• Not recommended for type 1 diabetes or diabetic ketoacidosis

Benefits

Evania M Tablet provides several benefits:

• Effective dual-action glucose control
• Helps reduce fasting and postprandial blood sugar
• Lower dose reduces risk of side effects
• Supports modest weight loss (due to empagliflozin)
• Low risk of hypoglycemia when used appropriately
• Improves treatment adherence with combination therapy

Possible Side Effects

Common side effects include:

• Nausea, diarrhea, abdominal discomfort
• Increased urination
• Urinary tract infections
• Genital fungal infections

Less common side effects:

• Dizziness
• Weakness
• Vitamin B12 deficiency (long-term use)

Serious side effects:

• Lactic Acidosis
• Diabetic Ketoacidosis
• Kidney function impairment

Precautions

• Take with meals to minimize stomach upset
• Maintain adequate hydration
• Monitor kidney function regularly
• Avoid excessive alcohol intake
• Use cautiously in elderly patients
• Temporarily discontinue before surgery or contrast imaging

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Evania M may interact with:

• Diuretics (risk of dehydration)
• Insulin or sulfonylureas (risk of hypoglycemia)
• Alcohol (increased risk of lactic acidosis)
• Iodinated contrast agents

Storage

Store in a cool, dry place below 30°C, protected from light and moisture. Keep out of reach of children.