Famiclav Tablet 250 mg + 62.5 mg is a combination antibiotic formulation containing Cefuroxime Axetil and Clavulanic Acid. This dual-action medicine is designed to provide enhanced antibacterial coverage by combining the proven efficacy of a second-generation cephalosporin with a beta-lactamase inhibitor. It is commonly prescribed for the treatment of various mild to moderate bacterial infections caused by susceptible and resistant organisms.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Cefuroxime Axetil: 250 mg

• Clavulanic Acid: 62.5 mg

Pharmacological Action

Cefuroxime Axetil is a prodrug that is converted in the body into its active form, cefuroxime. It exerts its antibacterial effect by inhibiting bacterial cell wall synthesis, leading to bacterial cell death. Clavulanic Acid works by inhibiting beta-lactamase enzymes produced by certain bacteria, which would otherwise inactivate cefuroxime. This combination extends the antibacterial spectrum and improves efficacy against resistant strains.

Indications

Famiclav Tablet 250 mg + 62.5 mg is indicated for the treatment of infections caused by beta-lactamase-producing and susceptible bacteria, including:

• Upper and lower respiratory tract infections such as sinusitis, bronchitis, tonsillitis, and pneumonia

• Ear, nose, and throat infections including otitis media and pharyngitis

• Urinary tract infections

• Skin and soft tissue infections

• Dental and other localized bacterial infections

• Other uncomplicated to moderately severe bacterial infections as advised by a physician

Dosage and Administration

• Adults: One tablet twice daily, or as directed by a physician

• Tablets should be taken after meals to improve absorption and reduce gastrointestinal discomfort

The duration of therapy depends on the severity and type of infection and should be completed as prescribed to prevent the development of antibiotic resistance.

Benefits and Advantages

• Broad-spectrum antibacterial activity

• Effective against beta-lactamase-producing bacteria

• Enhanced efficacy compared to cefuroxime alone

• Suitable for a wide range of community-acquired infections

• Convenient oral tablet form improves patient compliance

Safety and Precautions

Famiclav Tablet is generally well tolerated when used under medical supervision. Common side effects may include nausea, diarrhea, vomiting, abdominal discomfort, or headache. These effects are usually mild and transient.

• Contraindicated in patients with known hypersensitivity to cephalosporins or clavulanic acid

• Use with caution in patients with a history of penicillin allergy

• Prolonged use may result in superinfection with non-susceptible organisms

• Use during pregnancy and breastfeeding only if clearly indicated by a healthcare professional

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Concomitant use with antacids may reduce the absorption of Cefuroxime Axetil. Maintaining an appropriate time gap is recommended when such medications are required.

Storage

• Store below 30°C

• Protect from light and moisture

• Keep out of reach of children

• Do not use after the expiry date

Pack Information

Famiclav Tablet 250 mg + 62.5 mg is available in blister packs designed to ensure product stability, accurate dosing, and ease of use.