Famomax Tablet 20 mg contains Famotidine, a well-established histamine H₂-receptor antagonist used for the treatment and prevention of acid-related gastrointestinal disorders. It effectively reduces gastric acid secretion, thereby providing relief from symptoms associated with excessive stomach acid such as heartburn, indigestion, acid reflux, and epigastric pain. Famomax Tablet is widely prescribed due to its proven efficacy, good safety profile, and suitability for both short-term and long-term management of acid-peptic diseases.

By decreasing acid production, Famomax Tablet promotes healing of acid-damaged tissues and prevents recurrence of ulcers and reflux-related complications. It is suitable for adults and is often used when lifestyle modification and antacids alone are insufficient.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition and Therapeutic Class

Each tablet contains:

• Famotidine 20 mg

Therapeutic Class:
H₂-receptor antagonist (Anti-ulcerant)

Indications

Famomax Tablet 20 mg is indicated for the treatment and prevention of:

• Duodenal ulcer

• Benign gastric ulcer

• Gastroesophageal reflux disease (GERD)

• Zollinger–Ellison syndrome and other pathological hypersecretory conditions

• Symptomatic relief of heartburn and acid indigestion

• Prevention of ulcer recurrence

It is also used for acid suppression in hospitalized patients when oral therapy is appropriate.

Pharmacology

Famotidine competitively inhibits histamine at H₂-receptors of the gastric parietal cells. This action results in reduced basal and stimulated secretion of gastric acid, as well as a decrease in gastric volume and hydrogen ion concentration. Famotidine suppresses acid secretion stimulated by food, histamine, gastrin, and pentagastrin.

Compared to earlier H₂-receptor antagonists, Famotidine is more potent and has a longer duration of action, allowing for convenient once- or twice-daily dosing. It has minimal effect on gastric motility, pancreatic secretion, and serum prolactin levels. Famotidine does not significantly interfere with cytochrome P450 enzymes, reducing the risk of clinically relevant drug interactions.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Dosage and Administration

Dosage should be individualized based on the condition being treated:

• Duodenal ulcer: 40 mg once daily at bedtime or 20 mg twice daily

• Gastric ulcer: 40 mg once daily at bedtime

• GERD: 20 mg twice daily

• Hypersecretory conditions: Initial dose 20 mg every 6 hours, adjusted as needed

Famomax Tablet may be taken with or without food. Dose adjustment is required in patients with severe renal impairment.

Drug Interactions

Famotidine has a low potential for drug interactions. However:

• Antacids may reduce the absorption of Famotidine if taken simultaneously

• Drugs requiring an acidic gastric environment for absorption may have reduced bioavailability

Patients should consult a healthcare professional before combining medications.

Contraindications

Famomax Tablet is contraindicated in patients with:

• Known hypersensitivity to Famotidine or other H₂-receptor antagonists

• History of allergic reactions to any component of the formulation

Side Effects

Famomax Tablet is generally well tolerated. Common side effects may include:

• Headache

• Dizziness

• Constipation or diarrhea

Rare side effects include confusion (especially in elderly or critically ill patients), skin rash, fatigue, and elevated liver enzymes.

Use in Pregnancy and Lactation

Famotidine crosses the placenta and is excreted in breast milk. It should be used during pregnancy and lactation only if clearly needed and prescribed by a physician after assessing the benefit-risk ratio.

Precautions and Warnings

• Gastric malignancy should be excluded before initiating therapy for ulcers

• Use with caution in patients with renal impairment

• Elderly patients may be more sensitive to CNS effects

Storage Conditions

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.