Tenobis Plus Tablet 5 mg+6.25 mg is a fixed-dose combination of Bisoprolol Fumarate 5 mg and Hydrochlorothiazide 6.25 mg, formulated for the effective treatment of hypertension (high blood pressure). This combination therapy offers a dual mechanism of action to help achieve better blood pressure control in patients who require more than one medication.

High blood pressure is a major risk factor for cardiovascular diseases such as heart attack, stroke, heart failure, and kidney damage. Tenobis Plus works by reducing the workload on the heart while simultaneously eliminating excess fluid from the body, thereby lowering blood pressure and improving overall cardiovascular health.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Bisoprolol Fumarate 5 mg

• Hydrochlorothiazide 6.25 mg

Mechanism of Action

Bisoprolol is a selective beta-1 adrenergic receptor blocker that primarily acts on the heart. It reduces heart rate and cardiac output, leading to a decrease in blood pressure. By limiting the effects of stress hormones such as adrenaline, it helps maintain steady heart function.

Hydrochlorothiazide is a thiazide diuretic that promotes the excretion of sodium and water through the kidneys. This reduces blood volume and lowers peripheral vascular resistance, contributing further to blood pressure reduction.

Together, these two components provide complementary and sustained antihypertensive effects.

Indications

Tenobis Plus Tablet 5 mg+6.25 mg is indicated for:

• Management of essential hypertension

• Patients inadequately controlled with monotherapy

• Long-term blood pressure control to reduce cardiovascular risk

It may be used as initial therapy in certain patients or after dose titration of individual components.

Dosage and Administration

• The recommended dose is one tablet once daily or as directed by a physician.

• Preferably taken in the morning due to the diuretic component.

• Swallow the tablet whole with water.

• It may be taken with or without food.

Do not discontinue treatment abruptly without medical advice.

Benefits

• Effective dual-action blood pressure control

• Reduces heart rate and fluid retention

• Lowers risk of heart attack and stroke

• Convenient once-daily dosing

• Improves adherence through combination therapy

Precautions

• Regular monitoring of blood pressure, heart rate, and electrolyte levels is advised.

• Use cautiously in patients with asthma, diabetes, kidney disease, or gout.

• Hydrochlorothiazide may cause electrolyte imbalances, particularly low potassium levels.

• Not recommended in severe bradycardia or advanced heart block without specialist supervision.

• Avoid use during pregnancy unless prescribed by a healthcare provider.

Ensure regular follow-up visits during treatment.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects may include:

• Dizziness or lightheadedness

• Fatigue

• Slow heart rate

• Increased urination

• Electrolyte disturbances

• Mild gastrointestinal discomfort

Seek immediate medical attention if severe weakness, irregular heartbeat, breathing difficulty, or allergic reactions occur.

Storage

• Store below 30°C

• Keep in a cool, dry place

• Protect from moisture and direct sunlight

• Keep out of reach of children

Tenobis Plus Tablet 5 mg+6.25 mg offers a balanced and effective combination approach for managing hypertension and promoting long-term cardiovascular protection under medical supervision.