Fix-A DS Capsule 400 mg (Cefixime Trihydrate)

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Fix-A DS Capsule 400 mg contains Cefixime Trihydrate, a third-generation cephalosporin antibiotic used for the treatment of a broad range of bacterial infections in adults and children above 12 years. This double-strength (DS) formulation provides a higher dose in a single capsule, allowing for convenient once-daily or twice-daily administration depending on the severity of the infection. Cefixime acts by interfering with bacterial cell wall synthesis, leading to bacterial cell death, making it highly effective against both Gram-positive and Gram-negative bacteria.

Fix-A DS Capsule is suitable for the treatment of respiratory tract infections, urinary tract infections, throat and ear infections, and other systemic bacterial infections caused by susceptible microorganisms. Its oral capsule form ensures precise dosing, rapid absorption, and reliable therapeutic outcomes.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Fix-A DS Capsule 400 mg is indicated for the treatment of infections caused by susceptible bacteria, including:

  • Upper and lower respiratory tract infections – bronchitis, pneumonia, sinusitis

  • Urinary tract infections (UTIs) – cystitis, pyelonephritis

  • Throat and ear infections – pharyngitis, tonsillitis, otitis media

  • Gastrointestinal infections caused by sensitive bacterial strains

  • Skin and soft tissue infections under medical supervision

It should only be used in confirmed or strongly suspected bacterial infections to prevent antibiotic resistance.

Mechanism of Action

  • Bacterial cell wall synthesis inhibition: Cefixime binds to penicillin-binding proteins (PBPs), preventing the cross-linking of peptidoglycan chains in the bacterial cell wall.

  • Bactericidal effect: Disruption of the cell wall weakens bacteria and leads to cell lysis and death.

  • Broad-spectrum activity: Cefixime is effective against various Gram-negative bacteria such as Escherichia coli, Haemophilus influenzae, and selected Gram-positive bacteria including Streptococcus species.

Dosage and Administration

The recommended dosage should be determined by a healthcare professional based on the patient’s age, weight, and infection severity:

  • Adults and children over 12 years: 400 mg orally once daily or 200 mg twice daily, depending on clinical condition

  • Capsules should be swallowed whole with water and may be taken with or without food

  • The full course of therapy should be completed even if symptoms improve early to prevent recurrence and antibiotic resistance

  • Duration typically ranges from 5 to 10 days, but may vary depending on the infection type and physician’s instructions

Benefits and Features

  • Provides effective treatment for a wide range of bacterial infections

  • Double-strength formulation allows convenient dosing

  • Broad-spectrum activity against Gram-positive and Gram-negative bacteria

  • Rapid absorption ensures reliable therapeutic effect

  • Suitable for adults and children above 12 years under medical supervision

Side Effects

Fix-A DS Capsule 400 mg is generally well tolerated. Some patients may experience:

Precautions and Warnings

  • Use only under the guidance of a healthcare professional

  • Contraindicated in patients with a history of cephalosporin or penicillin allergy

  • Monitor for antibiotic-associated diarrhea or signs of superinfection

  • Dose adjustments may be necessary in patients with renal impairment

  • Keep out of reach of children to avoid accidental overdose

Storage Conditions

Store Fix-A DS Capsule 400 mg in a cool, dry place below 30°C, protected from moisture and sunlight. Keep capsules in their original packaging until use.

Fix-A DS Capsule 400 mg is a reliable, broad-spectrum cephalosporin antibiotic for treating various bacterial infections, offering convenient double-strength dosing, effective bacterial eradication, and excellent patient compliance.

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Fix-A DS Capsule 400 mg (Cefixime Trihydrate)
Fix-A DS Capsule 400 mg (Cefixime Trihydrate)
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