Flumetol (with device) Inhalation Capsule 50 mcg + 250 mcg is a combination inhalation therapy that includes Salmeterol and Fluticasone Propionate. It comes with a dedicated inhalation device to ensure accurate and effective delivery of medication directly into the lungs.
This strength is typically used for patients who need moderate-dose anti-inflammatory therapy along with sustained bronchodilation for better control of chronic respiratory conditions.
রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন
Composition
Each inhalation capsule contains:
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Salmeterol 50 mcg
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Fluticasone Propionate 250 mcg
For inhalation use only using the supplied device.
Mechanism of Action
Flumetol works through a dual mechanism:
Salmeterol
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Stimulates beta-2 adrenergic receptors in airway smooth muscle
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Produces long-acting bronchodilation (lasting up to 12 hours)
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Helps keep airways open and improves breathing
Fluticasone Propionate
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Reduces inflammation and swelling in the bronchial tubes
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Decreases mucus production
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Prevents airway hyper-responsiveness
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Helps reduce frequency of exacerbations
Together, they provide long-term control of airway obstruction and inflammation.
Indications
Flumetol (with device) is indicated for:
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Asthma
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Moderate to severe persistent asthma
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Chronic Obstructive Pulmonary Disease
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Patients requiring combination therapy for long-term control
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Prevention of frequent asthma or COPD exacerbations
Dosage and Administration
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Usually inhaled once or twice daily as prescribed
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Insert capsule into the device and pierce before inhalation
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Inhale deeply through the mouthpiece
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Do not swallow the capsule
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Rinse mouth after use to reduce risk of oral infections
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Use regularly for best results
Benefits
Flumetol (with device) provides several benefits:
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Dual-action therapy: bronchodilation + inflammation control
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Improves lung function and breathing
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Reduces frequency and severity of respiratory attacks
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Convenient and accurate delivery with included device
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Supports long-term respiratory stability
Possible Side Effects
Common side effects include:
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Throat irritation
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Hoarseness
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Cough
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Dry mouth
Less common side effects:
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Oral thrush (fungal infection)
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Headache
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Tremor or palpitations (from salmeterol)
Serious side effects (rare):
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Adrenal Suppression
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Paradoxical bronchospasm
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Severe allergic reactions
Precautions
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Not intended for relief of sudden asthma attacks
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Rinse mouth after each use
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Use cautiously in patients with cardiovascular disease
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Do not stop treatment abruptly
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Ensure proper inhaler technique for effective delivery
Drug Interactions
Flumetol may interact with:
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Strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
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Other bronchodilators or corticosteroids
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Beta-blockers (may reduce bronchodilator effect)
Storage
Store in a cool, dry place below 30°C, away from moisture and sunlight. Keep capsules in their original packaging until use.