Pidogrel Plus Tablet 75 mg + 75 mg is a fixed-dose combination of Clopidogrel 75 mg and Aspirin 75 mg, two antiplatelet agents that work together to prevent blood clot formation. This dual antiplatelet therapy (DAPT) is widely used in the management of cardiovascular diseases, particularly after acute coronary events and coronary stent placement.

The combination provides enhanced protection against clot formation compared to single antiplatelet therapy, thereby reducing the risk of heart attack, stroke, and other thrombotic complications.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Benefits

• Dual antiplatelet action for stronger clot prevention

• Reduces risk of heart attack and stroke

• Essential after coronary stent placement

• Improves outcomes in acute coronary syndrome

• Convenient fixed-dose combination for better compliance

Indications

Pidogrel Plus Tablet is indicated for:

• Acute coronary syndrome (ACS)

• Post–percutaneous coronary intervention (PCI) with stent placement

• Prevention of recurrent myocardial infarction

• Prevention of ischemic stroke

• High-risk patients with established atherosclerotic cardiovascular disease.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Dosage and Administration

• The usual recommended dose is one tablet once daily or as prescribed by a physician.

• Should be taken with water, preferably after food to reduce gastric irritation.

• Do not crush or chew unless advised.

• Treatment duration depends on the patient’s clinical condition and cardiologist’s recommendation.

Do not discontinue therapy abruptly without medical advice, as this may increase the risk of thrombosis.

Mechanism of Action

Clopidogrel inhibits the P2Y12 ADP receptor on platelets, preventing platelet activation and aggregation.

Aspirin inhibits cyclooxygenase-1 (COX-1), reducing thromboxane A2 production, which further prevents platelet aggregation.

Together, these two mechanisms provide synergistic inhibition of platelet function, significantly lowering the risk of clot formation.

Safety Information

Contraindications:

• Active bleeding (e.g., peptic ulcer, intracranial hemorrhage)

• Hypersensitivity to clopidogrel, aspirin, or NSAIDs

• Severe liver disease

Warnings and precautions:

• Increased risk of bleeding

• Use cautiously in patients with gastrointestinal disorders

• Inform doctor before surgery or dental procedures

• Avoid concurrent use with other anticoagulants or NSAIDs unless prescribed

Common side effects may include:

• Gastric irritation

• Bruising

• Nosebleeds

• Indigestion

Seek immediate medical attention if unusual or prolonged bleeding occurs.

Storage

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.