Peflox Tablet 400 mg contains Pefloxacin Mesylate Dihydrate, a broad-spectrum fluoroquinolone antibiotic used to treat a variety of bacterial infections. Pefloxacin works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. This inhibition prevents bacterial growth and leads to the elimination of the infection.

Peflox is effective against both Gram-positive and Gram-negative bacteria, making it a versatile option for infections affecting the urinary tract, respiratory system, gastrointestinal tract, and skin. The 400 mg tablet formulation allows for precise dosing and is convenient for adult patients under the supervision of a healthcare professional.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Peflox Tablet 400 mg is indicated for the treatment of:

• Urinary tract infections, including complicated and uncomplicated cases

• Respiratory tract infections, such as bronchitis and pneumonia

• Skin and soft tissue infections

• Bone and joint infections

• Gastrointestinal infections caused by susceptible bacteria

• Sexually transmitted infections, including gonorrhea caused by susceptible strains

Treatment should be guided by clinical evaluation, microbiological testing, and susceptibility of the infecting organism.

Dosage and Administration

• The usual adult dose is 400 mg orally twice daily, or as prescribed by the physician.

• Tablets should be taken with a full glass of water.

• Peflox may be taken with or without food, but maintaining adequate hydration is recommended to prevent potential crystalluria.

• Complete the full course of therapy even if symptoms improve early, to prevent bacterial resistance and recurrence of infection.

Dosage adjustments may be required in patients with impaired kidney function or in elderly patients.

Benefits of Peflox Tablet 400 mg

• Broad-spectrum antibacterial activity against a variety of infections

• Rapidly inhibits bacterial DNA replication, promoting effective clearance of infection

• Convenient oral tablet for accurate dosing

• Helps prevent progression of localized infections to systemic infections

• Well-established efficacy and safety profile

Possible Side Effects

Common side effects may include:

• Nausea, vomiting, or diarrhea

• Abdominal discomfort

• Headache or dizziness

• Mild skin rash

Less common but serious side effects may include:

• Tendon inflammation or rupture, especially in elderly patients or those on corticosteroids

• Peripheral neuropathy

• Central nervous system effects such as confusion or seizures

• Prolongation of the QT interval (heart rhythm disturbance)

Patients should report any severe or persistent symptoms immediately.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Avoid use in patients with known hypersensitivity to fluoroquinolones.

• Use cautiously in elderly patients, children, and patients with kidney disease.

• Adequate hydration is essential during therapy to prevent kidney-related complications.

• Avoid excessive exposure to sunlight or UV light due to risk of photosensitivity reactions.

• Not recommended during pregnancy or breastfeeding unless clearly prescribed by a healthcare professional.

• Drug interactions should be considered, especially with antacids, sucralfate, or multivitamins containing zinc or iron, which may reduce absorption.

Storage

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children. Do not use after the expiration date.

Peflox Tablet 400 mg provides an effective oral treatment for bacterial infections, offering broad-spectrum coverage and reliable clinical outcomes when used under medical supervision.