Gabarol CR Tablet 165 mg contains Pregabalin in a controlled-release (CR) formulation, specially designed to provide sustained and consistent relief from nerve-related disorders. This formulation allows the medication to be released gradually over an extended period, helping maintain stable drug levels in the body. It is widely prescribed for neuropathic pain, seizure disorders, and anxiety conditions, offering improved patient compliance through once-daily dosing.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Pregabalin 165 mg (Controlled Release)
• Dosage Form: Controlled-release tablet

Indications

Gabarol CR Tablet 165 mg is indicated for the management of:

• Neuropathic pain (including diabetic neuropathy and post-herpetic neuralgia)
• Nerve pain due to spinal cord injury
• Adjunctive therapy for partial seizures
• Generalized anxiety disorder (GAD)
• Fibromyalgia and chronic pain syndromes

Mechanism of Action

Pregabalin acts by binding to specific calcium channels in the central nervous system, reducing the release of neurotransmitters such as glutamate, norepinephrine, and substance P. This action decreases abnormal electrical activity in the brain and interrupts pain signal transmission. The controlled-release formulation ensures a prolonged therapeutic effect, minimizing peaks and troughs in drug concentration.

Dosage and Administration

• Take as prescribed by a registered healthcare professional.
• Typically administered once daily, preferably after food in the evening.
• Swallow the tablet whole with water; do not crush, chew, or break it.
• Maintain a consistent dosing schedule for optimal effectiveness.
• Do not discontinue suddenly without medical guidance to avoid withdrawal symptoms.

Benefits

• Provides extended and consistent relief from neuropathic pain
• Convenient once-daily dosing enhances patient adherence
• Helps in seizure control when used with other antiepileptic drugs
• Reduces anxiety and improves sleep quality
• Minimizes fluctuations in drug levels, improving tolerability

Possible Side Effects

Common side effects may include:

• Dizziness
• Drowsiness
• Fatigue
• Blurred vision
• Dry mouth
• Weight gain
• Peripheral edema (swelling of hands or feet)

These side effects are usually mild to moderate and may improve over time. Consult a doctor if they persist or worsen.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use cautiously in patients with kidney impairment; dose adjustment may be necessary.
• Avoid alcohol as it can increase sedation and dizziness.
• Not recommended during pregnancy or breastfeeding unless advised by a physician.
• May impair mental alertness; avoid driving or operating machinery if affected.
• Inform your doctor about all ongoing medications and underlying health conditions.

Storage

• Store below 30°C in a cool, dry place
• Protect from light and moisture
• Keep out of reach of children.