Glitin M Tablet combines Linagliptin 2.5 mg and Metformin Hydrochloride 1000 mg, offering a dual-action oral therapy for type 2 diabetes mellitus. This combination helps patients achieve better blood sugar control by targeting different aspects of glucose regulation. Linagliptin enhances insulin secretion and reduces glucagon levels in a glucose-dependent manner, while Metformin improves insulin sensitivity and reduces hepatic glucose production. Together, they provide effective glycemic control with reduced risk of hypoglycemia.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Linagliptin 2.5 mg
• Metformin Hydrochloride 1000 mg
• Dosage Form: Tablet

Indications

Glitin M Tablet is indicated for:

• Type 2 diabetes mellitus in adults
• Patients inadequately controlled with diet, exercise, and single antidiabetic agents
• Combination therapy for improved glycemic control

Mechanism of Action

• Linagliptin: Inhibits DPP-4 enzyme, increasing levels of incretin hormones (GLP-1, GIP), which stimulate insulin secretion and suppress glucagon release in response to meals.
• Metformin: Reduces hepatic glucose production, improves peripheral glucose uptake, and enhances insulin sensitivity.

The combination provides complementary mechanisms to maintain fasting and postprandial blood glucose within target ranges.

Dosage and Administration

• Take as prescribed by a healthcare professional.
• Usually administered once or twice daily, with meals to reduce gastrointestinal side effects.
• Swallow the tablet whole with water; do not crush or chew.
• Regular monitoring of blood glucose levels is recommended.
• Maintain a consistent diet and exercise regimen for optimal results.

Benefits

• Effective control of fasting and postprandial blood sugar
• Reduces the risk of hypoglycemia due to glucose-dependent action of Linagliptin
• Enhances insulin sensitivity and lowers liver glucose output
• Convenient combination therapy reduces pill burden
• Supports weight-neutral or weight-reducing effects

Possible Side Effects

Common side effects may include:

• Gastrointestinal disturbances (nausea, diarrhea, abdominal discomfort)
• Headache
• Nasopharyngitis (cold-like symptoms)
• Mild hypoglycemia (especially when combined with sulfonylureas)

Seek immediate medical attention if severe side effects such as lactic acidosis (rare) or pancreatitis occur.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use cautiously in patients with kidney or liver impairment.
• Not suitable for type 1 diabetes or diabetic ketoacidosis.
• Monitor renal function regularly due to Metformin component.
• Inform your doctor about all medications and medical history.
• Use during pregnancy or breastfeeding only under medical supervision.

Storage

• Store below 30°C in a dry, cool place
• Protect from light and moisture
• Keep out of reach of children.