Imanix Tablet 100 mg contains Imatinib Mesylate, a targeted anticancer medication widely used in the treatment of certain blood cancers and solid tumors. It belongs to the class of tyrosine kinase inhibitors (TKIs), which work by blocking abnormal proteins responsible for uncontrolled cancer cell growth.

This lower-strength formulation allows flexible dose adjustment and is often used in combination dosing regimens or for patients requiring gradual titration.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each film-coated tablet contains:

• Imatinib Mesylate equivalent to Imatinib 100 mg

Mechanism of Action

Imatinib selectively inhibits specific tyrosine kinases such as BCR-ABL, c-KIT, and platelet-derived growth factor receptor (PDGFR). These enzymes play a critical role in the growth and proliferation of cancer cells. By blocking these pathways, Imatinib suppresses tumor growth and promotes apoptosis (programmed cell death).

Indications

Imanix Tablet 100 mg is indicated for:

• Chronic myeloid leukemia (CML)
• Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL)
• Gastrointestinal stromal tumors (GIST)
• Myelodysplastic/myeloproliferative disorders
• Hypereosinophilic syndrome
• Dermatofibrosarcoma protuberans

Dosage and Administration

• To be taken orally as prescribed by an oncologist
• Usually taken with food and a full glass of water
• Tablets should be swallowed whole; do not crush or chew
• Dose depends on disease type, stage, and patient response
• Often used in combination with other strengths to achieve the required dose

Contraindications

Imanix Tablet should not be used in:

• Known hypersensitivity to Imatinib or any excipients
• Severe liver impairment without medical supervision
• Pregnancy and breastfeeding unless clearly advised by a specialist

Side Effects

Common side effects include:

• Nausea and vomiting
• Fluid retention (edema)
• Muscle cramps
• Diarrhea
• Fatigue
• Skin rash

Serious side effects may include:

• Severe edema or pleural effusion
• Liver toxicity
• Bone marrow suppression
• Cardiac complications (rare)

Precautions

• Regular monitoring of blood counts and liver function is required
• Use cautiously in patients with liver, kidney, or heart disease
• Monitor for signs of fluid retention
• Avoid pregnancy during treatment
• Maintain adequate hydration

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Imanix Tablet may interact with:

• CYP3A4 inhibitors or inducers (affect drug levels)
• Anticoagulants (require monitoring)
• Other anticancer agents
• Grapefruit products (may increase drug concentration)

Storage Conditions

• Store below 30°C in a dry place
• Protect from light and moisture
• Keep out of reach of children.