Insul R Injection 100 IU/ml contains recombinant DNA (rDNA) human insulin, a short-acting insulin used for the management of diabetes mellitus. It is primarily used to control high blood glucose levels, especially around meal times, and is an important component of insulin therapy in both outpatient and hospital settings.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Insulin Human (rDNA) 100 IU/ml

Mechanism of Action

Insulin Human (rDNA) acts by mimicking endogenous insulin produced by the pancreas. It facilitates the uptake of glucose into muscle and fat cells and reduces hepatic glucose production. This results in a decrease in blood glucose levels. Being short-acting, it is particularly effective in controlling postprandial (after-meal) glucose spikes.

Indications

Insul R Injection is indicated for:

• Type 1 diabetes mellitus
• Type 2 diabetes mellitus when oral antidiabetic agents are insufficient
• Control of post-meal blood glucose levels
• Diabetic ketoacidosis (as part of hospital treatment protocols)
• Gestational diabetes requiring insulin therapy
• Management of hyperglycemia in hospitalized patients

Dosage and Administration

• Administered via subcutaneous injection
• May be given intravenously in hospital settings under strict medical supervision
• Typically injected 30 minutes before meals
• Dosage is individualized based on blood glucose monitoring, diet, and clinical response
• Common injection sites include abdomen, thigh, or upper arm
• Rotate injection sites regularly to prevent lipodystrophy

Possible Side Effects

Common side effects include:

• Hypoglycemia (most common)
• Weight gain
• Injection site reactions (redness, swelling, or irritation)
• Lipodystrophy at injection sites

Less common but serious effects:

• Severe hypoglycemia leading to confusion, seizures, or loss of consciousness
• Allergic reactions
• Hypokalemia (low potassium levels)

Precautions

• Regular blood glucose monitoring is essential
• Do not skip meals after insulin administration
• Alcohol may increase the risk of hypoglycemia
• Dose adjustments may be required during illness, stress, or dietary changes
• Use cautiously in patients with kidney or liver impairment

Contraindications

• Hypoglycemia episodes
• Known hypersensitivity to human insulin or any component of the formulation

Drug Interactions

• Corticosteroids may increase blood glucose levels
• Beta-blockers may mask symptoms of hypoglycemia
• Oral antidiabetic drugs may enhance insulin effect
• Thyroid hormones and diuretics may affect glucose control

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage Instructions

• Store in a refrigerator at 2°C to 8°C
• Do not freeze
• Protect from heat and direct sunlight
• Once in use, may be kept at room temperature for a limited period as per guidance

Important Notes

Insul R Injection 100 IU/ml (rDNA Human Insulin) is a reliable short-acting insulin used for effective control of blood glucose levels, particularly after meals. Proper administration timing, dietary control, and regular monitoring are essential for safe and effective diabetes management.