Iriban SR 200 mg contains Mebeverine, a musculotropic antispasmodic agent specifically designed to relieve abdominal cramps and spasms associated with irritable bowel syndrome (IBS) and other gastrointestinal disorders. By relaxing the smooth muscles of the gut, Iriban SR helps restore normal bowel movement, alleviates colicky pain, and improves overall digestive comfort. The sustained-release formulation allows for convenient twice-daily dosing, providing longer-lasting relief.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Class

• Anticholinergics

• Musculotropic antispasmodics

Composition

Each sustained-release capsule contains:

• Mebeverine 200 mg

Indications

Iriban SR 200 mg is indicated for the symptomatic management of:

• Irritable bowel syndrome (IBS)

• Chronic irritable colon

• Spastic constipation

• Mucous colitis

• Colicky abdominal pain

• Persistent non-specific diarrhea

It provides targeted relief by reducing gut muscle spasms and associated discomfort.

Pharmacology

Mebeverine acts as a musculotropic antispasmodic, relaxing the smooth muscles of the gastrointestinal tract without affecting normal motility. This action helps relieve abdominal cramps and discomfort caused by spasms, particularly in IBS. Unlike systemic anticholinergics, Mebeverine primarily targets the gut, reducing the risk of widespread side effects.

Dosage and Administration

Adults, elderly, and children over 10 years:

• Mebeverine SR 200 mg capsule: 1 capsule twice daily, preferably 20 minutes before meals

• Mebeverine 135 mg tablet: 1 tablet three times daily

• Continue treatment until symptoms improve; dosage may be gradually reduced after several weeks

Missed Dose:

• Take as soon as possible unless it is almost time for the next dose

• Do not double the dose to compensate

Pediatric Use:

• Not recommended for children under 10 years

Contraindications

• Hypersensitivity to Mebeverine or any other ingredients in the formulation

Side Effects

• Generally well tolerated

• Rare reactions may include:

  • Skin rash

  • Urticaria

  • Angioedema

Drug Interactions

• No significant drug interactions have been established

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Pregnancy and Lactation

• Animal studies show no evidence of teratogenicity

• Administer only under medical supervision during pregnancy

• Mebeverine is not excreted in breast milk at therapeutic doses

Precautions and Warnings

• Use caution in patients with porphyria or a history of allergic reactions to anticholinergic drugs

• Overdosage may lead to central nervous system excitability; symptomatic treatment and gastric lavage are recommended

Storage Conditions

• Store below 30°C

• Protect from light

• Keep out of reach of children

Use in Special Populations

• Children under 10 years: Not recommended

• Elderly: Use standard adult dosing unless otherwise directed

Mode of Action

Mebeverine directly relaxes the smooth muscles of the gastrointestinal tract, reducing spasms and relieving cramp-related pain, while preserving normal gut motility.