Irigate Solution 1.50% contains Glycine, an amino acid solution used primarily as an irrigating fluid during urological, laparoscopic, and endoscopic surgical procedures. It is designed to maintain clear visibility in the operative field, facilitate safe tissue manipulation, and minimize complications during procedures such as transurethral resection of the prostate (TURP), bladder surgeries, and other minimally invasive interventions.

Surgical irrigation solutions play a critical role in flushing blood, tissue debris, and other fluids from the operative site, preventing obstruction of the surgeon’s view. Glycine-based solutions, like Irigate 1.50%, are non-electrolytic and hypoosmotic, making them suitable for use with monopolar electrosurgical devices without conducting electricity, thereby reducing the risk of intraoperative complications.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each 100 ml of Irigate Solution contains:

• Glycine 1.50% – an amino acid-based non-electrolyte solution for irrigation purposes

The solution is sterile, pyrogen-free, and formulated for use in surgical settings to maintain tissue integrity and ensure patient safety.

Mechanism of Action

Irigate Solution works through the following mechanisms:

• Tissue irrigation: Flushes blood, cellular debris, and surgical fluids from the operative field, improving visibility for the surgeon.

• Non-electrolytic nature: Safe for use with monopolar electrosurgical instruments, preventing electrical conduction and tissue injury.

• Hypoosmotic properties: Minimizes tissue edema while providing a clear visual field.

• Tissue compatibility: Glycine is a naturally occurring amino acid, reducing the risk of irritation or cytotoxicity during procedures.

By maintaining a clear operative field and protecting tissues, Irigate Solution contributes to safer and more efficient surgical outcomes.

Indications

Irigate Solution 1.50% is indicated for:

• Irrigation during urological surgeries, including TURP and bladder procedures

• Laparoscopic and endoscopic surgeries requiring clear visibility of the operative site

• Use as an irrigating fluid in procedures involving monopolar electrosurgical devices

• Flushing and cleaning tissue surfaces during minimally invasive interventions

Benefits

• Maintains a clear operative field for precise surgical work

• Safe for use with monopolar electrosurgical instruments due to non-electrolytic formulation

• Minimizes tissue irritation and damage

• Reduces the risk of surgical complications

• Sterile and pyrogen-free for safe intraoperative use

Dosage and Administration

• Administration: Used intraoperatively as an irrigating fluid under the supervision of a trained surgeon or healthcare professional.

• Volume: Depends on the procedure and surgical requirements; the solution should be used in sufficient volume to maintain visibility and flush debris.

• Handling: Use aseptically. Discard any unused solution to maintain sterility.

Precautions

• Use only under professional medical supervision during surgical procedures

• Monitor for fluid overload, especially in patients with cardiac or renal impairment

• Avoid contact with eyes or injection; this solution is strictly for intraoperative irrigation

• Do not mix with other electrolyte solutions unless recommended by the surgical team

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Irigate Solution 1.50% is generally safe when used as intended. Potential issues include:

• Rare fluid absorption leading to hyponatremia or glycine-related toxicity during prolonged irrigation

• Mild tissue irritation if solution leaks outside the operative site

• Electrolyte imbalance if excessively absorbed

Careful intraoperative monitoring minimizes these risks.

Storage

Store in a cool, dry place below 30°C, away from direct sunlight. Keep the container sealed until use and out of reach of unauthorized personnel.

Irigate Solution 1.50% provides a safe, effective, and reliable means to maintain a clear operative field during urological and minimally invasive surgical procedures, supporting optimal surgical outcomes.