Ivaten Tablet 5 mg contains Ivabradine, a selective heart rate-lowering medication used primarily for the treatment of chronic stable angina and heart failure with reduced ejection fraction (HFrEF). Ivabradine acts directly on the sinoatrial (SA) node, the heart’s natural pacemaker, to reduce heart rate without affecting myocardial contractility or blood pressure.

By controlling the heart rate, Ivaten Tablet 5 mg helps reduce myocardial oxygen demand, relieve angina symptoms, improve exercise tolerance, and support better cardiac efficiency in patients with heart failure. This makes it a valuable option for patients who areintolerant to beta-blockers or need additional heart rate control alongside other therapies.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Ivaten Tablet 5 mg is indicated for:

• Chronic stable angina pectoris in adults with normal sinus rhythm

• Heart failure with reduced ejection fraction (HFrEF) in patients with elevated heart rate

• Patients requiring heart rate control who cannot tolerate beta-blockers

It can be prescribed as monotherapy or in combination with other cardiovascular medications, depending on the patient’s condition and physician’s assessment.

Mechanism of Action

Ivabradine selectively inhibits the If (“funny”) current in the SA node. This current is responsible for generating spontaneous pacemaker activity in the heart. By blocking this current, Ivabradine slows the heart rate while preserving myocardial contractility, conduction, and blood pressure.

Unlike beta-blockers or calcium channel blockers, Ivabradine does not negatively impact blood pressure or cardiac output, making it suitable for patients with low blood pressure or compromised ventricular function. Slower heart rate allows more time for ventricular filling and coronary perfusion, which improves overall cardiac efficiency.

Dosage and Administration

• The usual starting dose is 5 mg twice daily, which may be adjusted based on heart rate and clinical response.

• Tablets should be taken orally with water, preferably at the same times each day.

• Swallow the tablet whole; do not crush, chew, or split.

• Regular monitoring of heart rate and symptoms is recommended to ensure optimal dosing.

Dosage adjustments may be required in elderly patients, those with liver impairment, or patients concurrently using certain other medications.

Precautions

Before taking Ivaten Tablet 5 mg, patients should inform their doctor if they have:

• Severe bradycardia (heart rate <50 bpm)

• Sick sinus syndrome, sinoatrial block, or heart conduction disorders

• Atrial fibrillation or other arrhythmias

• Severe hypotension or unstable angina

• Liver impairment

Sudden discontinuation should be avoided, and patients should follow scheduled check-ups to monitor heart rate and blood pressure.

Use in Pregnancy and Lactation

Ivabradine should be used during pregnancy only if clearly necessary and prescribed by a physician. It is not recommended for use during breastfeeding due to limited safety data.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects include:

• Bradycardia (slow heart rate)

• Dizziness or fatigue

• Headache

• Visual disturbances such as transient luminous phenomena (phosphenes)

• Nausea

Rare but serious side effects may include severe bradycardia or atrial fibrillation. Immediate medical attention is required if serious adverse effects occur.

Storage

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.

Ivaten Tablet 5 mg provides effective heart rate reduction, improving angina symptoms and cardiac performance in patients with heart failure under careful medical supervision.