Jaktor XR Tablet 11 mg contains Tofacitinib in an extended-release (XR) formulation. It is an oral Janus kinase (JAK) inhibitor used for the treatment of various chronic autoimmune and inflammatory diseases such as rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. The extended-release design allows for once-daily dosing, providing sustained therapeutic effects and improved patient convenience.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Tofacitinib 11 mg (Extended Release)

Mechanism of Action

Tofacitinib selectively inhibits Janus kinase (JAK) enzymes, which are involved in the signaling pathways of cytokines responsible for inflammation and immune responses. By blocking these pathways, Jaktor XR reduces the activity of the immune system, thereby decreasing inflammation, pain, and tissue damage associated with autoimmune diseases.

Indications

Jaktor XR Tablet 11 mg is indicated for:

• Moderate to severe rheumatoid arthritis in adults
• Active psoriatic arthritis
• Moderate to severe ulcerative colitis
• Other autoimmune conditions as prescribed by a healthcare professional

Dosage and Administration

• The recommended dose is 11 mg once daily.
• Swallow the tablet whole; do not crush, split, or chew.
• It can be taken with or without food.
• Dosage adjustments may be required for patients with kidney or liver impairment.
• Always follow your physician’s guidance for optimal results.

Benefits

• Provides continuous 24-hour symptom control
• Reduces joint inflammation, stiffness, and pain
• Improves physical function and quality of life
• Convenient once-daily dosing enhances treatment adherence
• Helps manage symptoms of ulcerative colitis effectively

Side Effects

Common side effects include:

• Headache
• Nasopharyngitis (common cold symptoms)
• Diarrhea
• Nausea
• Elevated cholesterol levels

Serious side effects may include:

• Serious infections (e.g., tuberculosis, viral or fungal infections)
• Blood clots (deep vein thrombosis, pulmonary embolism)
• Decreased white or red blood cell counts
• Liver enzyme abnormalities

Immediate medical attention is required if severe reactions occur.

Precautions and Warnings

• Screen for latent infections, including tuberculosis, before initiating therapy.
• Use cautiously in patients with a history of cardiovascular disease or blood clots.
• Regular monitoring of blood counts, liver enzymes, and lipid profile is recommended.
• Not recommended during pregnancy or breastfeeding unless prescribed.
• Increased risk of malignancies has been associated with long-term use.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Jaktor XR may interact with:

• Other immunosuppressive medications
• Strong CYP3A4 inhibitors (e.g., certain antifungals)
• CYP3A4 inducers (e.g., rifampicin)

Inform your healthcare provider about all medicines you are taking to avoid interactions.

Storage

• Store below 30°C in a cool and dry place
• Protect from light and moisture
• Keep out of reach of children.