Lenva Capsule 10 mg contains Lenvatinib Mesylate, an oral anti-cancer medicine belonging to the tyrosine kinase inhibitor (TKI) class. It is used in the treatment of advanced and progressive cancers by blocking specific pathways that promote tumor growth and blood vessel formation. This higher-strength formulation is used in patients who require an increased therapeutic dose under strict oncologist supervision.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Lenvatinib Mesylate equivalent to Lenvatinib 10 mg

Mechanism of Action

Lenvatinib works by inhibiting multiple receptor tyrosine kinases involved in cancer cell proliferation and angiogenesis. It blocks VEGFR, FGFR, PDGFR, KIT, and RET signaling pathways, reducing tumor blood supply and slowing cancer growth. This multi-targeted action helps control disease progression in various advanced malignancies.

Indications

Lenva Capsule 10 mg is indicated for:

• Radioiodine-refractory differentiated thyroid cancer
• Advanced renal cell carcinoma
• Hepatocellular carcinoma (primary liver cancer)
• Selected cases of endometrial carcinoma (in combination therapy)

Dosage and Administration

• Taken orally once daily, with or without food
• Capsules should be swallowed whole with water; do not crush or open
• Dosage is individualized based on body weight, condition, and tolerance
• Must be taken strictly as prescribed by an oncologist
• Regular medical monitoring is essential during therapy

Benefits

• Inhibits multiple cancer growth pathways simultaneously
• Helps slow tumor progression and metastasis
• Improves treatment outcomes in advanced cancers
• Oral administration increases convenience and adherence
• Effective in patients with limited treatment options

Side Effects

Common side effects may include:

• Hypertension (high blood pressure)
• Fatigue and weakness
• Diarrhea
• Decreased appetite and weight loss
• Nausea and vomiting

Serious side effects may include:

• Liver dysfunction
• Kidney impairment and proteinuria
• Bleeding or clotting complications
• Heart failure or cardiac issues
• Gastrointestinal perforation (rare but serious)

Immediate medical attention is required for severe symptoms.

Precautions and Warnings

• Blood pressure must be closely monitored during treatment
• Regular liver and kidney function tests are required
• Not recommended during pregnancy or breastfeeding
• Use cautiously in patients with cardiovascular disease
• May impair wound healing; inform doctor before surgery

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Lenva Capsule may interact with:

• CYP3A4 enzyme inducers or inhibitors
• Antihypertensive medicines
• Anticoagulants and antiplatelet drugs

Always inform the healthcare provider about all medications and supplements being taken.

Storage

• Store below 30°C in a cool, dry place
• Protect from moisture and direct light
• Keep out of reach of children.