Levoxin TS Eye Drop 1.50% is a broad-spectrum fluoroquinolone ophthalmic solution containing Levofloxacin, designed for the treatment of bacterial infections of the eye and ear. It is highly effective against both Gram-positive and Gram-negative bacteria, providing rapid relief from inflammation, redness, and discomfort caused by bacterial infections. Levoxin TS is commonly prescribed for conjunctivitis, keratitis, blepharitis, and external ear infections.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Class

Fluoroquinolone Antibiotic (Ophthalmic / Otic Preparation)

Pharmacology

Levofloxacin, the active ingredient, is a third-generation fluoroquinolone that acts by inhibiting bacterial DNA gyrase and topoisomerase IV. These enzymes are essential for bacterial DNA replication, transcription, and repair, and their inhibition results in bactericidal activity.

Levoxin TS Eye Drop exhibits:

• Rapid penetration into ocular tissues

• Activity against common ocular pathogens such as:

  • Staphylococcus aureus

  • Staphylococcus epidermidis

  • Streptococcus pneumoniae

  • Haemophilus influenzae

  • Pseudomonas aeruginosa

Its high potency makes it effective in treating both acute and chronic bacterial infections of the eye and ear.

Indications

Levoxin TS Eye Drop 1.50% is indicated for:

• Bacterial conjunctivitis (including cases caused by S. aureus, S. epidermidis, S. pneumoniae)

• Bacterial keratitis

• Blepharitis and other eyelid infections

• External bacterial ear infections (otitis externa)

• Prophylaxis of bacterial infections in ocular surgery or procedures, as determined by a healthcare provider

Dosage and Administration

• Adults and children: Instill 1–2 drops into the affected eye(s) every 2–4 hours for the first two days, followed by every 4–6 hours until the infection resolves.

• For ear infections: Apply 2–3 drops in the affected ear(s) 2–3 times daily, or as directed by a healthcare provider.

• Treatment duration typically ranges from 7 to 14 days, depending on the severity of the infection.

• Ensure proper hygiene during application and avoid contact with the dropper tip to prevent contamination.

Contraindications

• Known hypersensitivity to Levofloxacin, other fluoroquinolones, or any component of the formulation

• Avoid in patients with a history of severe allergic reactions to quinolones

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Side Effects

Levoxin TS Eye Drop is generally well tolerated, with adverse effects being mild and transient:

• Eye irritation, burning, or stinging upon instillation

• Redness or itching of the eye

• Rarely, blurred vision or photophobia

Precautions and Warnings

• Use caution in patients with severe renal impairment, as systemic absorption is minimal but may occur with prolonged use.

• Avoid contact lenses during treatment unless recommended by a physician.

• Discontinue use if allergic reactions or worsening symptoms occur.

Pregnancy and Lactation

• Use during pregnancy only if clearly needed; safety has not been fully established

• Caution is advised for nursing mothers, although systemic absorption is low

Storage Conditions

• Store in a cool, dry place below 30°C, away from light

• Keep out of reach of children

• Once opened, use within the period recommended by the manufacturer

Mode of Action

Levoxin TS Eye Drop 1.50% works by inhibiting bacterial DNA replication, which halts bacterial growth and leads to rapid bacterial cell death. Its broad-spectrum activity and high ocular penetration make it highly effective for treating both acute and chronic infections of the eye and external ear.