Lifil-E 400 mg is a high-potency vitamin E preparation used to prevent and treat vitamin E deficiency and support overall health. Vitamin E is a fat-soluble antioxidant that protects cellular membranes and oxygen-sensitive substances such as vitamin A and vitamin C from oxidative damage. Lifil-E 400 mg helps maintain cardiovascular health, supports healthy skin and hair, and protects red blood cells from oxidative stress.

It is also used therapeutically in conditions such as hemolytic anemia, heavy metal toxicity, hepatotoxin poisoning, and during oxygen therapy. Lifil-E 400 mg is suitable for both adults and children as a dietary supplement or adjunct therapy for specific clinical conditions.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Class

Vitamin-E Preparation

Indications

Dietary Supplement:

• Vitamin E deficiency due to impaired absorption

• Increased vitamin E requirements from diets rich in polyunsaturated fats

• Support for healthy hair and skin

• Antioxidant protection against oxidative stress

• Hemolytic anemia resulting from vitamin E deficiency

Therapeutic Use:

• Cardiovascular disease and prevention of oxidative damage

• Heavy metal poisoning

• Hepatotoxin poisoning

• Hemolytic anemia

• Oxygen therapy

• Nutritional deficiency states

Pharmacology

Vitamin E (tocopherol) acts as a powerful antioxidant in the body. It protects polyunsaturated fatty acids in cellular membranes and oxygen-sensitive vitamins, preventing oxidative damage.

• In premature neonates, vitamin E deficiency can lead to irritability, edema, thrombosis, and hemolytic anemia.

• In adults and children, low serum tocopherol levels can result in creatinuria, ceroid deposition, muscle weakness, decreased erythrocyte survival, and increased susceptibility to oxidative hemolysis.

By neutralizing free radicals, vitamin E helps maintain healthy cells, tissues, and organs while reducing oxidative stress-related complications.

Dosage and Administration

Dosage depends on the purpose of supplementation and age:

• Cardiovascular health: 400–800 IU per day

• Deficiency in adults: 200–400 IU per day

• Deficiency in children: 200 IU per day

• Thalassemia: 800 IU per day

• Sickle-cell anemia: 400 IU per day

• Skin and hair improvement: 200–400 IU per day (topical use also effective)

• Chronic cold in adults: 200 IU per day

Always follow physician guidance for dosage, especially for therapeutic purposes.

Drug Interactions

• Vitamin E may impair absorption of vitamin A

• May interfere with vitamin K function

• Potentiates the anticoagulant effect of warfarin, increasing bleeding risk

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Contraindications

• No absolute contraindications have been reported

• Use caution in patients at risk of thrombosis, such as those on estrogen therapy

Possible Side Effects

• Overdosage (>1 g/day) may cause:

  • Fatigue

  • Diarrhea

  • Myopathy

  • Mild hypertension

Most side effects are mild and reversible upon dose adjustment.

Pregnancy & Lactation

• Safe when used at recommended doses

• High-dose safety is not established; avoid exceeding recommended amounts

Precautions

• May increase the risk of thrombosis in susceptible patients

• Monitor patients on anticoagulants or estrogen therapy for bleeding risks

Storage

Store in a dry, cool place, away from light and heat. Keep out of reach of children.

Use in Special Populations

• Safe for children when used as recommended

• Suitable for adults and pregnant or lactating women within recommended doses.