Linamide Capsule 25 mg contains Lenalidomide, a potent immunomodulatory and anticancer agent used in the management of specific hematological malignancies. It is structurally related to thalidomide and exerts anti-cancer effects by modulating immune activity, inhibiting tumor growth, and reducing angiogenesis. This higher-strength formulation is used in selected patients under strict oncologist supervision.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Lenalidomide 25 mg

Mechanism of Action

Lenalidomide works through multiple anti-cancer mechanisms:

• Enhances immune system response against malignant cells
• Inhibits formation of new blood vessels (anti-angiogenesis) that supply tumors
• Suppresses proliferation of abnormal blood cells
• Promotes programmed cell death (apoptosis) of cancer cells

These combined actions help control disease progression in hematologic cancers.

Indications

Linamide Capsule 25 mg is indicated for:

• Multiple myeloma (in combination with dexamethasone)
• Myelodysplastic syndromes with deletion 5q abnormality
• Mantle cell lymphoma (after prior therapy)
• Selected cases of follicular lymphoma (combination therapy)

Dosage and Administration

• Taken orally once daily, with or without food
• Capsule should be swallowed whole with water; do not open or crush
• Dosage is individualized based on disease type, tolerance, and blood counts
• Treatment is administered in cycles as directed by an oncologist
• Regular monitoring is mandatory during therapy

Benefits

• Helps control progression of multiple hematologic cancers
• Enhances immune-mediated destruction of cancer cells
• Reduces tumor growth and spread
• Improves survival outcomes in selected patients
• Effective as part of combination chemotherapy regimens

Side Effects

Common side effects may include:

• Fatigue and weakness
• Diarrhea or constipation
• Rash or skin irritation
• Decreased blood cell counts (anemia, neutropenia, thrombocytopenia)

Serious side effects:

• Blood clots (deep vein thrombosis, pulmonary embolism)
• Severe infections due to immune suppression
• Liver function abnormalities
• Severe allergic reactions

Immediate medical attention is required if serious symptoms occur.

Precautions and Warnings

• Highly teratogenic: strictly contraindicated in pregnancy
• Mandatory pregnancy prevention program required for women of childbearing potential
• Regular complete blood count (CBC) monitoring is essential
• Increased risk of thromboembolism; preventive measures may be required
• Use cautiously in patients with kidney disease or clotting disorders

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Linamide Capsule may interact with:

• Corticosteroids (e.g., dexamethasone)
• Anticoagulants
• Other immunosuppressive or anticancer agents

Always inform your healthcare provider about all ongoing medications.

Storage

• Store below 30°C in a dry place
• Protect from light and moisture
• Keep out of reach of children.