Locol Tablet 20 mg contains Atorvastatin Calcium, a lipid-lowering agent belonging to the statin class. It is used to manage high cholesterol levels and reduce the risk of cardiovascular diseases such as heart attack and stroke. This higher-strength formulation is typically prescribed when lower doses are insufficient to achieve target lipid levels.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Atorvastatin Calcium
• Strength: 20 mg
• Dosage Form: Oral tablet

Mechanism of Action

Atorvastatin works by inhibiting the enzyme HMG-CoA reductase in the liver, which plays a key role in cholesterol production. This leads to:

• Reduced synthesis of LDL (bad cholesterol)
• Increased removal of LDL from the blood
• Moderate increase in HDL (good cholesterol)
• Lower triglyceride levels

These combined effects help reduce plaque formation in blood vessels.

Indications

Locol Tablet 20 mg is indicated for:

• Hypercholesterolemia
• Mixed dyslipidemia
• Prevention of cardiovascular events (heart attack, stroke)
• Patients at high risk due to diabetes, hypertension, or family history
• Cases requiring stronger lipid-lowering therapy

Dosage and Administration

• Dose is individualized based on lipid profile and clinical response
• Usually taken once daily, with or without food
• Best taken at the same time each day
• Regular monitoring of cholesterol levels is recommended
• Follow physician’s instructions strictly

Benefits

• More potent reduction of LDL cholesterol
• Helps prevent heart attack and stroke
• Improves overall lipid balance
• Once-daily convenient dosing
• Well-established cardiovascular protection

Side Effects

Common side effects may include:

• Muscle pain or weakness
• Headache
• Nausea
• Abdominal discomfort
• Mild elevation of liver enzymes

Less common but serious effects:

• Rhabdomyolysis (rare but serious muscle breakdown)
• Liver dysfunction
• Allergic reactions
• Increased blood sugar levels

Precautions and Warnings

• Use only under medical supervision
• Regular liver function monitoring is recommended
• Report unexplained muscle pain immediately
• Avoid excessive alcohol consumption
• Caution in patients with liver disease
• Not recommended during pregnancy or breastfeeding

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Use in Special Populations

• Pregnancy: Contraindicated
• Lactation: Not recommended
• Pediatrics: Only under specialist supervision
• Elderly: May require careful monitoring

Storage

• Store below 25°C
• Protect from light and moisture
• Keep in original packaging
• Keep out of reach of children.