Lotemycin Suspension is a sterile ophthalmic preparation combining Loteprednol Etabonate 0.5%, a corticosteroid, and Tobramycin 0.3%, a broad-spectrum aminoglycoside antibiotic. This dual-action formulation is indicated for the treatment of steroid-responsive inflammatory ocular conditions where bacterial infection or risk of bacterial infection exists.

The combination provides effective control of inflammation while simultaneously eliminating susceptible bacterial pathogens. Lotemycin is specially formulated for ophthalmic use and should be administered under medical supervision.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Class

• Corticosteroid (Ophthalmic)

• Aminoglycoside Antibiotic (Ophthalmic)

• Anti-inflammatory and Antibacterial Combination

Indications

Lotemycin Suspension is indicated for:

• Steroid-responsive inflammatory conditions of the eye

• Post-operative ocular inflammation

• Bacterial conjunctivitis associated with inflammation

• Blepharitis and keratitis where infection is suspected or confirmed

• Prevention of infection in ocular inflammatory disorders

It is particularly useful when inflammation and bacterial infection occur simultaneously or when there is a high risk of bacterial contamination.

Pharmacology & Mode of Action

Loteprednol Etabonate:

• A topical corticosteroid that inhibits inflammatory mediators such as prostaglandins and leukotrienes.

• Reduces redness, swelling, itching, and ocular discomfort.

• Designed with a “soft steroid” structure to minimize intraocular pressure elevation compared to traditional corticosteroids.

Tobramycin:

• A bactericidal aminoglycoside antibiotic.

• Inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit.

• Effective against a wide range of gram-negative and certain gram-positive bacteria commonly responsible for ocular infections.

The combination ensures rapid symptomatic relief while addressing the underlying bacterial cause.

Dosage & Administration

• Shake well before use.

• Instill 1–2 drops into the affected eye(s) every 4–6 hours.

• In severe infections, dosing may be increased initially as directed by the physician.

• Avoid touching the dropper tip to any surface to prevent contamination.

Duration of treatment should be determined by the healthcare provider.

Contraindications

• Hypersensitivity to Loteprednol, Tobramycin, or any component of the formulation

• Viral diseases of the cornea and conjunctiva (e.g., herpes simplex)

• Fungal infections of ocular structures

• Untreated mycobacterial eye infections

Side Effects

Common side effects may include:

• Transient burning or stinging upon instillation

• Eye irritation

• Blurred vision

Prolonged use may lead to:

• Increased intraocular pressure

• Cataract formation

• Secondary fungal infections

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions & Warnings

• Prolonged corticosteroid use may increase intraocular pressure; monitor regularly.

• Use cautiously in patients with glaucoma.

• Discontinue if signs of hypersensitivity occur.

• Not for injection or oral use.

• Avoid contact lens use during active infection unless advised by a physician.

Pregnancy & Lactation

• Use during pregnancy only if clearly needed.

• Caution is advised during breastfeeding; consult a healthcare provider.

Storage Conditions

• Store below 25°C.

• Protect from light.

• Keep tightly closed and out of reach of children.

Lotemycin Suspension 0.5% + 0.3% provides effective anti-inflammatory and antibacterial therapy in ocular conditions, ensuring rapid symptom relief while combating infection for improved eye health and recovery.