Minirin Melt Tablet 120 mcg contains Desmopressin Acetate, a synthetic analogue of the natural antidiuretic hormone (ADH), vasopressin. It is used to control excessive urine production in conditions related to impaired water balance. The melt formulation is designed to dissolve under the tongue without water, offering convenient administration and accurate dosing.

Desmopressin increases water reabsorption in the kidneys, thereby reducing urine output and improving symptoms associated with frequent urination. The 120 mcg strength is typically prescribed when a higher therapeutic dose is required, based on clinical evaluation and patient response.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Benefits

• Controls excessive urination
  Helps reduce high urine output in conditions such as diabetes insipidus and nocturnal polyuria.

• Effective management of bedwetting
  Supports the treatment of primary nocturnal enuresis in children.

• Convenient melt formulation
  Sublingual tablet dissolves without water, making it suitable for children and patients with swallowing difficulties.

• Targeted renal action
  Provides antidiuretic effects with minimal impact on blood pressure.

Indications

Minirin Melt Tablet 120 mcg is indicated for:

• Primary nocturnal enuresis (bedwetting) in children over 5 years of age.

• Central diabetes insipidus.

• Nocturia due to nocturnal polyuria in adults, as advised by a healthcare professional.

Treatment should be initiated and supervised by a qualified physician.

Dosage and Administration

• Place the tablet under the tongue and allow it to dissolve completely.

• Do not chew or swallow the tablet whole.

• Fluid intake must be restricted from 1 hour before to at least 8 hours after taking the dose to reduce the risk of water retention and low sodium levels.

• Dosage depends on age, indication, and clinical response.

Strict adherence to medical guidance is essential for safe and effective treatment.

Mechanism of Action

Desmopressin selectively binds to V2 receptors in the renal collecting ducts, promoting water reabsorption and reducing urine production. Compared to natural vasopressin, it has minimal vasoconstrictive effect, making it safer for long-term use in indicated patients.

Safety Information

Contraindications:

• Hyponatremia or history of low sodium levels.

• Moderate to severe renal impairment.

• Habitual or psychogenic polydipsia.

Warnings and precautions:

• Risk of water retention and hyponatremia if fluid restriction is not maintained.

• Regular monitoring of serum sodium levels is recommended.

• Use cautiously in elderly patients and those with cardiovascular disease.

Common side effects may include headache, nausea, abdominal discomfort, and rarely, symptoms of low sodium such as confusion or seizures.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

Store below 30°C in a dry place, protected from moisture and light. Keep out of reach of children.