Mobifen Suppository 25 mg contains Diclofenac Sodium, a non-steroidal anti-inflammatory drug (NSAID) used for effective pain relief and reduction of inflammation. The rectal suppository formulation provides an alternative route of administration for patients who cannot take oral medication due to nausea, vomiting, or gastrointestinal sensitivity. It is suitable for acute pain management and inflammatory conditions, providing rapid and reliable analgesic action.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Diclofenac Sodium 25 mg

Mechanism of Action

Diclofenac Sodium inhibits cyclooxygenase (COX-1 and COX-2) enzymes, thereby reducing the production of prostaglandins—chemical mediators responsible for pain, inflammation, and fever. Rectal administration ensures effective absorption, bypassing the gastrointestinal tract, making it suitable for patients with oral intolerance.

Indications

Mobifen Suppository 25 mg is indicated for:

• Relief of moderate to severe acute pain
• Musculoskeletal pain (sprains, strains, arthritis)
• Post-operative pain management
• Pain due to inflammatory conditions
• Patients unable to tolerate oral NSAIDs

Dosage and Administration

• Adults: 1 suppository rectally 1–2 times daily, or as prescribed by a physician
• Insert gently into the rectum after cleaning the area
• Use the lowest effective dose for the shortest duration necessary
• Avoid exceeding the prescribed dose

Benefits

• Provides rapid pain relief and anti-inflammatory effect
• Suitable for patients who cannot take oral medication
• Convenient rectal administration
• Reduces swelling, stiffness, and discomfort in acute conditions
• Improves patient comfort and compliance

Side Effects

Common side effects:

• Mild rectal irritation or discomfort
• Nausea or abdominal discomfort
• Headache or dizziness

Serious side effects (rare):

• Gastrointestinal bleeding or ulceration
• Kidney or liver impairment
• Severe allergic reactions (rash, swelling, difficulty breathing)
• Cardiovascular complications with prolonged use

Precautions

• Use with caution in patients with kidney, liver, or gastrointestinal disorders
• Avoid prolonged use to reduce the risk of serious side effects
• Monitor renal and liver function if used long-term
• Elderly patients may be more susceptible to adverse effects
• Consult a doctor if pain persists or worsens

Contraindications

• Hypersensitivity to Diclofenac or other NSAIDs
• Active gastrointestinal bleeding or ulcer
• Severe renal or hepatic impairment
• History of NSAID-induced asthma
• Late pregnancy (third trimester)

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Diclofenac may interact with:

• Anticoagulants (e.g., warfarin) – increased risk of bleeding
• Other NSAIDs – increased risk of gastrointestinal complications
• ACE inhibitors or diuretics – may affect kidney function
• Corticosteroids – increased risk of ulcers or GI irritation

Storage

• Store below 30°C in a cool, dry place
• Protect from light and moisture
• Keep out of reach of children.