Neofloxin Injection 200 mg/100 ml contains Ciprofloxacin, a broad-spectrum fluoroquinolone antibiotic used for the treatment of a wide range of serious bacterial infections. It is specially formulated for intravenous (IV) infusion, making it suitable for hospitalized patients or those who are unable to take oral medications.

Ciprofloxacin works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication, transcription, repair, and recombination. This mechanism leads to rapid bacterial cell death, making Neofloxin Injection highly effective against many Gram-negative and Gram-positive pathogens.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Neofloxin Injection is indicated for the treatment of infections caused by susceptible microorganisms, including:

• Lower respiratory tract infections (e.g., pneumonia, bronchitis)

• Urinary tract infections (complicated and uncomplicated)

• Gastrointestinal infections, including enteric fever

• Skin and soft tissue infections

• Bone and joint infections

• Intra-abdominal infections (in combination with other appropriate agents)

• Septicemia and bacteremia

• Infections in immunocompromised patients

Dosage and Administration

Neofloxin Injection is administered by slow intravenous infusion, usually over a period of 60 minutes. Dosage depends on the severity of infection, renal function, and clinical condition of the patient.

• Typical adult dose: 200 mg to 400 mg every 12 hours

• Dose adjustment may be required in patients with renal impairment

Treatment duration varies based on the type and severity of infection and should be determined by a qualified healthcare professional.

Pharmacological Properties

Ciprofloxacin exhibits excellent tissue penetration and achieves high concentrations in urine, lungs, kidneys, prostate, and gastrointestinal tract. It has a rapid onset of action and a well-established safety and efficacy profile when used appropriately.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use with caution in patients with a history of tendon disorders related to fluoroquinolone therapy

• May increase the risk of QT interval prolongation

• Not recommended for use in children, adolescents, pregnant, or breastfeeding women unless clearly indicated

• Adequate hydration is advised during therapy

• Avoid concomitant use with drugs that may interact with ciprofloxacin unless supervised by a physician

Adverse Effects

Common side effects may include:

• Nausea, vomiting, diarrhea

• Headache or dizziness

• Injection site reactions

Serious but rare adverse effects include tendon rupture, peripheral neuropathy, and central nervous system effects.

Storage

• Store below 30°C

• Protect from light

• Do not freeze

• Keep out of reach of children

Presentation

Neofloxin Injection is supplied as a 200 mg Ciprofloxacin in 100 ml ready-to-use IV infusion, ensuring convenience, accuracy, and safety in hospital settings.