Renesis Tablet 100 mg contains Roxadustat, an oral hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor used in the management of anemia associated with chronic kidney disease (CKD). It works by stimulating the body’s natural erythropoietin production, improving red blood cell formation and increasing hemoglobin levels. This higher-strength formulation is used in patients requiring more intensive anemia control under specialist supervision.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Roxadustat 100 mg

Mechanism of Action

Roxadustat stabilizes hypoxia-inducible factor (HIF), which leads to:

• Increased endogenous erythropoietin production in the kidneys
• Enhanced absorption and utilization of iron from the gastrointestinal tract
• Improved red blood cell production in the bone marrow
• Correction of anemia associated with chronic kidney disease

This mechanism mimics the body’s natural response to low oxygen levels.

Indications

Renesis Tablet 100 mg is indicated for:

• Anemia associated with chronic kidney disease (CKD) in adults
• Patients on dialysis or non-dialysis CKD management (as prescribed by a nephrologist)

Dosage and Administration

• To be taken strictly under the supervision of a nephrologist
• Usually administered orally three times weekly or as directed
• Can be taken with or without food
• Dose is individualized based on hemoglobin response and iron status
• Regular monitoring of hemoglobin and iron parameters is essential

Benefits

• Effectively increases hemoglobin levels
• Reduces symptoms of anemia such as fatigue and weakness
• Improves oxygen delivery throughout the body
• Decreases reliance on injectable erythropoiesis-stimulating agents
• Enhances quality of life in CKD patients

Side Effects

Common side effects may include:

• Nausea or vomiting
• Diarrhea or constipation
• Dizziness
• Hypertension (high blood pressure)
• Peripheral edema (swelling in hands or feet)

Serious side effects require immediate medical attention and regular monitoring.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Regular monitoring of hemoglobin, iron levels, and cardiovascular status is required
• Use cautiously in patients with heart disease or hypertension
• Not recommended during pregnancy unless clearly necessary
• Inform your doctor about all concurrent medications
• Dose adjustment may be required based on clinical response

Storage

• Store below 30°C in a dry place
• Protect from light and moisture
• Keep out of reach of children.