Vintelix Tablet 5 mg contains Vortioxetine Hydrobromide, a novel antidepressant with a multimodal mechanism of action. It is primarily indicated for the treatment of major depressive disorder (MDD) in adults. Vintelix helps improve mood, emotional stability, and cognitive function associated with depression, making it a valuable option for long-term mental health management.

Vortioxetine is distinguished from conventional antidepressants by its combined action on serotonin receptors and serotonin reuptake inhibition. This dual activity contributes to effective symptom control while maintaining a favorable tolerability profile.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Class

Antidepressant (Serotonin modulator and stimulator)

Indications

Vintelix Tablet 5 mg is indicated for:

• Treatment of major depressive disorder (MDD) in adults

• Management of depressive symptoms such as low mood, loss of interest, anxiety, and impaired concentration

• Improvement of cognitive dysfunction associated with depression, including memory and executive function deficits

Pharmacology

Vortioxetine acts as a serotonin reuptake inhibitor and simultaneously modulates multiple serotonin receptor subtypes. It inhibits the serotonin transporter, increasing serotonin levels in the central nervous system. Additionally, it functions as an agonist, partial agonist, or antagonist at various serotonin receptors, enhancing neurotransmission involved in mood regulation and cognition. This multimodal activity is believed to contribute to its antidepressant efficacy and beneficial effects on cognitive symptoms of depression.

Dosage and Administration

• Recommended starting dose: 5 mg once daily

• The dose may be adjusted based on clinical response and tolerability

• Tablets may be taken with or without food

• Treatment should be continued as advised by a healthcare professional

Dose adjustments may be necessary in elderly patients or those with hepatic impairment.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Contraindications

Vintelix Tablet 5 mg is contraindicated in patients with:

• Hypersensitivity to vortioxetine or any excipients

• Concomitant use with monoamine oxidase inhibitors (MAOIs) or within 14 days of discontinuing an MAOI

Side Effects

Common side effects include:

• Nausea

• Headache

• Dizziness

• Dry mouth

• Diarrhoea or constipation

Less common side effects may include:

• Sleep disturbances

• Fatigue

• Sexual dysfunction

• Anxiety or restlessness

Most adverse effects are mild to moderate and tend to decrease with continued use.

Precautions and Warnings

• Monitor for worsening depression or suicidal thoughts, especially during initial therapy

• Use with caution in patients with a history of seizures or bleeding disorders

• Avoid abrupt discontinuation to reduce the risk of withdrawal symptoms

• Caution is advised when used with other serotonergic drugs due to the risk of serotonin syndrome

Pregnancy and Lactation

• Pregnancy: Use only if the potential benefit justifies the potential risk to the fetus

• Lactation: Caution is advised as vortioxetine may be excreted in breast milk

Storage Conditions

Store in a cool and dry place.
Protect from light and moisture.
Keep out of reach of children.