Nightus Tablet 3 mg contains Bromazepam, a short- to intermediate-acting benzodiazepine primarily used for the management of anxiety-related disorders and associated sleep disturbances. It exerts anxiolytic, sedative, muscle relaxant, and anticonvulsant properties, making it effective in relieving psychological tension, restlessness, and insomnia related to anxiety. Nightus Tablet is intended for short-term use under strict medical supervision due to the risk of dependence.

Therapeutic Class

Benzodiazepine
Anxiolytic and sedative-hypnotic agent

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Nightus Tablet 3 mg is indicated for the short-term treatment of:

• Anxiety disorders

• Severe stress-related anxiety

• Anxiety associated with depression

• Insomnia secondary to anxiety

• Psychosomatic and functional disorders where anxiety is a prominent symptom

It may also be used as a premedication in certain clinical situations as advised by a physician.

Pharmacology

Bromazepam is a benzodiazepine that acts on the central nervous system by enhancing the inhibitory effect of gamma-aminobutyric acid (GABA) at the GABA-A receptor. This action increases neuronal membrane permeability to chloride ions, resulting in hyperpolarization of nerve cells and reduced neuronal excitability. The overall effect is calming, anxiolytic, and sedative. Bromazepam is well absorbed after oral administration and is extensively metabolized in the liver, with metabolites excreted primarily via the kidneys.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Dosage and Administration

The dosage of Nightus Tablet should be individualized according to the severity of symptoms and patient response.

• The usual adult dose ranges from 1.5 mg to 3 mg, taken one to three times daily.

• For insomnia related to anxiety, it is often taken at night before bedtime.

Elderly or debilitated patients should start at lower doses. Treatment duration should generally be short and should not exceed the period recommended by the physician.

Contraindications

Nightus Tablet is contraindicated in patients with:

• Hypersensitivity to bromazepam or other benzodiazepines

• Severe respiratory insufficiency

• Severe hepatic impairment

• Sleep apnea syndrome

• Myasthenia gravis

Side Effects

Common side effects may include:

• Drowsiness

• Fatigue

• Dizziness

• Muscle weakness

• Reduced alertness or impaired coordination

Prolonged use may lead to tolerance, dependence, or withdrawal symptoms upon abrupt discontinuation.

Precautions and Warnings

Caution is required in patients with respiratory disorders, liver or kidney disease, depression, or a history of substance abuse. Nightus Tablet may impair the ability to drive or operate machinery. Abrupt cessation should be avoided; dose tapering is recommended to minimize withdrawal effects. Concomitant use with alcohol or other CNS depressants can enhance sedative effects and should be avoided.

Drug Interactions

Bromazepam may interact with other central nervous system depressants, including alcohol, opioids, antipsychotics, antidepressants, and sedative medications, leading to enhanced sedation and respiratory depression.

Pregnancy and Lactation

Nightus Tablet is not recommended during pregnancy due to potential risks to the fetus. Bromazepam may pass into breast milk; therefore, breastfeeding should be avoided during treatment unless clearly directed by a physician.

Storage Conditions

Store below 30°C in a cool, dry place, protected from light and moisture. Keep out of reach of children.